2018
DOI: 10.1002/dc.23950
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Cytodiagnosis of inflammatory myofibroblastic tumor: A report of three cases in infants

Abstract: Inflammatory myofibroblastic tumor is a tumor of intermediate grade with a low rate of metastasis. The tumor often mimics malignancy. There is sparse literature available describing the cytological findings of this rare condition. It often presents in infancy and childhood as an intra-abdominal mass. Here, we describe the cytological findings of three cases of inflammatory myofibroblastic tumor in infants aged 10 months, 4 months, and 15 months, respectively. While the first two cases are fine needle aspiratio… Show more

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Cited by 7 publications
(10 citation statements)
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“…ALK-1 positivity was associated with a better prognosis in our case according to some studies ( 14 ); other authors support that there was no correlation between the two variables ( 6 ). At least 50% of IMT presents AlK-1 positivity; this proportion increases in the primary cardiac tumor: this immunochemical marker facilitates the diagnostic process ( 15 , 16 ). Cytokeratin was negative; there was a weak immunopositivity of desmin.…”
Section: Discussionmentioning
confidence: 99%
“…ALK-1 positivity was associated with a better prognosis in our case according to some studies ( 14 ); other authors support that there was no correlation between the two variables ( 6 ). At least 50% of IMT presents AlK-1 positivity; this proportion increases in the primary cardiac tumor: this immunochemical marker facilitates the diagnostic process ( 15 , 16 ). Cytokeratin was negative; there was a weak immunopositivity of desmin.…”
Section: Discussionmentioning
confidence: 99%
“…It is extremely hard to have a definite pre-operative diagnosis of mesenteric IMT unless FNAC could be performed ( 20 ). Mesenteric IMT develops in both small and large bowel.…”
Section: Discussionmentioning
confidence: 99%
“…ALK plays a vital role in the prognosis and diagnosis of IMT. ALK-positive mesenteric IMT had a better prognosis and a lower rate of recurrence ( 20 ).…”
Section: Discussionmentioning
confidence: 99%
“…Although inflammatory myofibroblastic tumors may arise at any site, these tumors preferentially involve the abdominal cavity, lung, head and neck, and mediastinum. In children, there is a predilection for the abdominal cavity, especially omentum, mesentery, retroperitoneum, pelvis, or intrabdominal viscera [3][4][5][6][7][8].…”
Section: Introductionmentioning
confidence: 99%