Cytogenetic analysis of peripheral blood lymphocytes of occupational workers exposed to low levels of ionising radiation

Cytogenetic analysis in lymphocytes from radiation workers exposed to low level of ionizing radiation in radiotherapy, CT-scan and angiocardiography units

“…Several studies reported the presence of chromosomal aberrations in peripheral blood lymphocytes of persons chronically exposed to low doses of ionizing radiation [14][15][16]. Our results are in agreement with these studies, although like Ballardin et al [17] a significant increase in chromosome aberrations with respect to control was found for acentric fragments and not for dicentric and ring, probably due to the low doses of exposure of the individuals in the present study.…”

Chromosome Aberrations in Peripheral Blood Lymphocytes of Croatian Hospital Staff Occupationally Exposed to Low Levels of Ionising Radiation

“…Chung et al (14) did not find any significant association between age or cigarette smoking and any type of chromosomal aberrations. On the other hand, some studies indicate greater aberration frequency in smokers than in nonsmokers (12,28,29). Data from a study of Au et al (30) suggest that the lymphocytes of smokers made more errors in DNA repair than the cells of non-smokers.…”

The effects in mice of combined treatments to X-rays and antineoplastic drugs in the Comet assay

“…Some papers have described chromosomal aberrations, micronuclei and sister chromatid exchanges in the peripheral blood lymphocytes of hospital or nuclear power plant workers exposed occupationally to X-rays (Sabati et al, 1992;Kubelka et al, 1992b;Barquinero et al, 1993;Garaj-Vrhovac et al, 1997;Jha and Sharma, 1991;Balakrishnan and Rao, 1999;Cardoso et al, 2001), or anticancer drugs (Oestreicher et al, 1990;Sardas et al, 1991;Sessink et al, 1994;Fucic et al, 1998). Some authors have observed the induction of DNA damage measured in the Comet assay in peripheral lymphocytes of nurses handling antineoplastic drugs (Undeger et al, 1999;Maluf and Erdtmann, 2000).…”