2023
DOI: 10.47836/mjmhs.19.3.21
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Cytogenomic Profiling of Chronic Lymphocytic Leukaemia Patients Using DNA Microarray

Abstract: Introduction: Chronic lymphocytic leukaemia (CLL) is the most frequent adult leukaemia in the Western world. The clinical presentation varies greatly, from very indolent cases to those with aggressive and fast advancing disease. This variation has significant implications for clinical approaches, therapeutic tactics, and, ultimately, survival durations from diagnosis. Acquired chromosomal aberrations play a key role in CLL aetiology. Due to difficulty to obtain abnormal metaphases for analysis, few methods suc… Show more

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