1997
DOI: 10.1016/s0091-6749(97)70201-x
|View full text |Cite
|
Sign up to set email alerts
|

Cytokine levels and inflammatory responses in developing late-phase allergic reactions in the skin

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
3
1

Citation Types

9
19
0
1

Year Published

1999
1999
2019
2019

Publication Types

Select...
9

Relationship

0
9

Authors

Journals

citations
Cited by 40 publications
(29 citation statements)
references
References 21 publications
9
19
0
1
Order By: Relevance
“…CX3CL1 (fractalkine), I-309 (SCYA-1), IL-8 and Teck (SCYA-25) were found to be increased in AD. IL-8 is already known to be increased in the skin of AD patients [43], and serum levels are correlated with disease severity [44]. Interestingly, CX3CL1, I-309 and Teck are assumed to act on monocytes or dendritic cells [45].…”
Section: Discussionmentioning
confidence: 99%
“…CX3CL1 (fractalkine), I-309 (SCYA-1), IL-8 and Teck (SCYA-25) were found to be increased in AD. IL-8 is already known to be increased in the skin of AD patients [43], and serum levels are correlated with disease severity [44]. Interestingly, CX3CL1, I-309 and Teck are assumed to act on monocytes or dendritic cells [45].…”
Section: Discussionmentioning
confidence: 99%
“…IL-8 recruits both neutrophils and monocytes (Marie et al, 1999) and has been associated with a variety of acute inflammatory reactions (Garner et al, 1994;Ono et al, 1995;Strickland et al, 1997;Zweiman et al, 1997) and chronic skin diseases (Gearing et al, Biologic activity of IL-8/Ad5-induced protein. Human fibroblasts were infected with 20 PFU/cell of IL-8/Ad5 or LacZ/Ad5 and were cultured in serum-free medium for 48 hours, after which the supernatants were harvested.…”
Section: Discussionmentioning
confidence: 99%
“…In contrast, high levels of IL-8 have been detected during acute inflammatory reactions (Garner et al, 1994;Ono et al, 1995;Strickland et al, 1997;Zweiman et al, 1997); in chronic skin diseases such as psoriasis vulgaris (Gearing et al, 1990;Nickoloff et al, 1991;Anttila et al, 1992;Schrö der et al, 1992;Schulz et al, 1993;Gillitzer et al, 1991;Gillitzer et al, 1996), palmoplantar pustulosis (Anttila et al, 1992), and bullous pemphigoid (Schmidt, 1996); and in nonmelanoma and melanoma skin tumors (Hansen et al, 1991;Ciotti et al, 1995;Bornscheuer et al, 1996). However, the role of IL-8 in the pathogenesis of skin diseases has been difficult to elucidate because of the abundance of other cytokines that can induce IL-8 expression.…”
mentioning
confidence: 99%
“…However, it is conceivable that mast cells also have an important function in the later stages of allergic inflammation by their interactions with infiltrated inflammatory cells and notably with the eosinophils [1, 2]. In the past we have demonstrated that rat peritoneal mast cells activated by an IgE–dependent mechanism are partially desensitized to a similar reactivation for a few hours but do respond when exposed to non IgE–dependent activators such as compound 48/80 or substance P [3].…”
Section: Introductionmentioning
confidence: 99%