2016
DOI: 10.15448/1980-6108.2016.3.23399
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Cytokine measurements in Brazilian postmenopausal osteoporosis patients reveal high levels of IL-8

Abstract: Aims: Osteoporosis is a common disease that affects mostly women and has been associated with the immune system. The aims of this study were to evaluate the serum levels of inflammatory cytokines in women with postmenopausal osteoporosis and to investigate their relationship with clinical and laboratory parameters. Methods: This study recruited patients with postmenopausal osteoporosis (osteoporosis group) and non-osteoporotic postmenopausal women (control group) matched for age. All patients and controls had … Show more

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“…Cytokine is a strong stimulator of in vitro and in vivo bone resorption; thus, its inhibition may contribute to enhancing bone regeneration and healing in OP patients [ 74 ]. Similar, the Il-8 levels were increased in OP patients as well [ 75 ]. Obtained data support application of materials incorporated with APTES for the treatment of OP-affected bone due to their anti-inflammatory properties.…”
Section: Discussionmentioning
confidence: 73%
“…Cytokine is a strong stimulator of in vitro and in vivo bone resorption; thus, its inhibition may contribute to enhancing bone regeneration and healing in OP patients [ 74 ]. Similar, the Il-8 levels were increased in OP patients as well [ 75 ]. Obtained data support application of materials incorporated with APTES for the treatment of OP-affected bone due to their anti-inflammatory properties.…”
Section: Discussionmentioning
confidence: 73%