Cytologic Diagnosis on Aspirate from 1000 Salivary-Gland Tumours

Eneroth, C.-M.; Franzén, S.; Zajicek, J

doi:10.3109/00016486709123574

Cited by 88 publications

(54 citation statements)

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“…Regarding investigation in the present study, FNAC was done in all 32 cases (100%), of which 26 cases (81.25%) were positive, 2 cases (6.25%) were false negative and 4 cases were doubtful/unsatisfactory results, which also conforms to other studies 16 . Sialography was done in 2 cases in suspected sialolithiasis.…”

supporting

confidence: 70%

Management of salivary gland neoplasm study of 32 cases

Kafi¹,

Bhuyan²,

Bhuiyan³

et al. 2010

Bangladesh J Med Sci

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Objective: To study the clinical, radiological and histopathological characteristics along with the management outcome of salivary gland neoplasm. Materials and Methods: This study included thirty two patients (16 male and 16 female) with salivary gland tumours presented at Combined Military Hospital Dhaka, Apollo Hospital Dhaka and Ibn Sina Medical College and Hospital Dhaka from January 2006 to December 2009. The data of each patient included age, sex, presenting symptoms and signs, provisional diagnosis, preoperative investigations, operation notes, histopathological examination and state at follow up. Results: The mean age was 42.5 years. 14 (43.75%) patients presented at 5 th decade. Main presenting symptom was swelling (100%) followed by pain (18.75%). All patients underwent fine needle aspiration cytology which was conclusive in 26 patients (81.25%). Thirty one patients underwent surgical excision. 24 cases were parotid neoplasm and 8 cases were submandibular neoplasm. 20 patients (16 parotid and 4 submandibular) were pleomorphic adenoma. Conclusion: There is no substitute for detailed clinical history and examination in the assessment of salivary gland neoplasm. Imaging studies are probably academic but determine the extent of the disease. Early diagnosis, adequate and proper treatment improves the prognosis.

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supporting

confidence: 70%

Management of salivary gland neoplasm study of 32 cases

Kafi¹,

Bhuyan²,

Bhuiyan³

et al. 2010

Bangladesh J Med Sci

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“…Type-specific FNA cytologic diagnosis for neoplastic and nonneoplastic salivary gland lesions is possible in most cases, as is evident from the literature of the past three and a half decades [2,6,[10][11][12][13][14][15]. The lesions of salivary glands have been described for diagnostic purposes under five major headings: benign nonneoplastic lesions (benign aspirate, inflammatory lesions, reactive lymphoid tissue, benign cystic lesions, and lipomatous lesions), benign neoplasms, malignancies, atypical cytology, and inadequate material.…”

Section: Discussionmentioning

confidence: 85%

Role of Fine Needle Aspiration Cytology in the Diagnosis of Swellings in the Salivary Gland Regions: A Study of 712 Cases

Das¹,

Petkar²,

Al-Mane³

et al. 2004

Med Princ Pract

111

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Introduction: A mass in the salivary gland region often presents a diagnostic challenge with regard to its site of origin (salivary versus nonsalivary), benign or malignant nature, and tissue-specific diagnosis. The present study describes the utility of fine-needle aspiration (FNA) cytology in the diagnosis of these lesions. Subjects and Methods: Over a 6-year period (January 1994 to December 1999), 712 patients aged between 6 months and 91 years (median, 37 years) were subjected to FNA of swellings in their salivary gland regions. Male:female ratio was 1.28:1. The swellings were mostly located in the parotid (323 cases), submandibular (343 cases), and upper cervical region (27 cases). Swellings of oral (5 cases) and sublingual (2 cases) sites were rare. The lesions diagnosed by FNA cytology were compared among the major salivary glands. Cytologic diagnoses were correlated with histology in 45 cases. Results: Benign nonneoplastic lesions were the most common (73%), followed by neoplasms (20%), and those with atypical cytology (1%). Cytologic material was inadequate in 6% cases. Parotid gland region was involved more frequently by neoplasms (27.1%) than the submandibular gland region (13.7%, p < 0.0001). Inflammatory processes affected the submandibular gland region more commonly (42.0%) than the parotid (32.6%, p = 0.0164). Pleomorphic adenoma was the most common neoplasm (61.5%), followed by Warthin’s tumor (12.6%). Malignancies accounted for 10.5% of neoplasms. Frequency of involvement of parotid by Warthin’s tumor (16.7%) was significantly higher than that of submandibular gland (2.3%, p = 0.0191). However, the submandibular gland was more commonly affected by malignancy than the parotid gland (p = 0.0003). Sensitivity, specificity, and diagnostic accuracy of FNA cytology for all neoplastic lesions of the salivary gland were 94.6, 75.0, and 91.1%, respectively. The corresponding figures for malignancies were 60.0, 95.0, and 91.1%, respectively. Conclusion: FNA cytology is very useful for the diagnosis of salivary gland lesions. However, sampling and interpretation errors may occur. The low specificity for the diagnosis of neoplasms as a whole and the poor sensitivity for malignancies found in our study can be attributed to the relatively small number of benign nonneoplastic and malignancy cases with available histopathologic diagnoses.

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“…[1][2][3][4][6][7][8][9][10][11][12] The accuracy is relatively higher for benign than for malignant salivary gland neoplasms. 14 In our series there were two false negative cases: a benign diagnosis was made on FNA in the presence of a malignant salivary gland neoplasm.…”

Section: A B Cmentioning

confidence: 99%

“…[1][2][3][4][5][6][7][8][9][10][11][12] Superficial parotidectomy with preservation of the facial nerve is the procedure of choice in the management of most patients with pleomorphic adenoma (PA), whereas in adenoid cystic carcinoma (ACC), total or radical excision of the gland is usually performed, often with sacrifice of the facial nerve. 7,13 The histologic features of PA and ACC are distinctive and allow a definitive diagnosis in primary and metastatic sites.…”

mentioning

confidence: 99%