Cytologic Features of Ascites in Malignant Fibrous Histiocytoma of the Colon

Abstract

The cytologic features of ascitic fluid in a case of malignant fibrous histiocytoma (MFH) of the colon are described. At autopsy, two solid tumor masses were found around the ascending and transverse colon, accompanied by about 3,000 ml of ascites. Tumor cells had infiltrated diffusely into the outer layers of almost all of the gastrointestinal wall, simulating peritonitis carcinomatosa. Cytologic examination of the ascites revealed various kinds of tumor cells; short spindle‐like cells, multinucleated giant cells, and round cells with an invaginated nuclear margin, forming small clusters. These cytologic findings were considered to be very useful in the diagnosis of MFH, especially in cytologic examinations of ascites. ACTA PATHOL JPN 38: 921 ∼ 928, 1988.

Cytology of Langerhans Cell Histiocytosis in Effusions

“…Thus, clinically, the present case was obviously different from MFH and malignant histiocytosis, and the histologic findings suggested LCH. Cytologic features of MFH in ascites have been reported 8 ; an increase in and uneven distribution of chromatin were more prominent, and the nucleoli were larger than in our case.…”

Undifferentiated high-grade pleomorphic sarcoma of the colon: a rare case report and literature review

“…Studies were included per the following inclusion criteria: (1) clinical features of Studies with duplicate data or data not relevant to UPS were excluded. After the screening, only 20 cases were included (Table 2) [11][12][13][14][15][16][17][18][19][20][21][22][23][24][25][26][27][28][29][30]. The characteristics of UPS were analyzed in this study.…”

Pediatric Undifferentiated Pleomorphic Sarcoma of the Cecum

“…To our knowledge, only 14 cases of cecal or ascending colon UPS are reported in the literature. [2][3][4][5][6][7][8][9][10][11][12][13][14] The classification and subdivision of these tumors went through several iterations until the World Health Organization 2002 classification eliminated the term MFH and replaced it with UPS. 1 UPSs most commonly occur later in life, usually the sixth and seventh decades, 15 and account for approximately 20% of all soft-tissue sarcomas.…”

“…7,8,10 Laboratory findings at diagnosis may be normal or may show elevated inflammatory markers, leukocytosis, and anemia. 2,3,8,9 Diagnosis is based on a combination of microscopic features and immunohistochemical staining techniques used to rule out other cell lines of origin. Lesions are typically characterized by pleomorphic, spindle-shaped cells with bizarre cytology and nuclear atypia.…”