Cytological diagnosis of cardiac masses with ultrasound guided fine needle aspirates

Pedro, Brigite; Linney, Chris; Navarro-Cubas, Xavier; Stephenson, Hannah; Dukes‐McEwan, J.; Gelzer, Anna R.; Kraus, Marc S.

doi:10.1016/j.jvc.2015.09.002

Cited by 17 publications

(18 citation statements)

References 16 publications

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“…Studies comparing cytology to histopathology have shown up to a 90% agreement . Fine‐needle aspiration can be used on both superficial and deeper lesions when combined with advanced imaging technology such as ultrasound, computed tomography, or fluoroscopy . A disadvantage of FNA is that a definitive diagnosis cannot always be made based solely on FNA samples without histologic architecture.…”

Section: Introductionmentioning

confidence: 99%

Fine‐needle aspiration of cutaneous, subcutaneous, and intracavitary masses in dogs and cats using 22‐ vs 25‐gauge needles

Arai

Rist

Clancey

et al. 2019

Veterinary Clinical Pathol

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Background Fine‐needle aspiration (FNA) is a common procedure as a diagnostic tool in veterinary medicine. However, it is unclear whether the gauge of the needle affects the quality of cytology. Objective This study compared the quality of cytologic samples obtained via FNA using 22‐ or 25‐gauge needles. Methods Fine‐needle aspiration was performed on 50 masses (cutaneous, subcutaneous, or intracavitary) obtained from client‐owned animals. The size of the needle was randomly assigned using either of the following two sequences: 22‐25‐22 gauge or 25‐22‐25 gauge. Samples were evaluated by two board‐certified clinical pathologists to assess cellularity, blood contamination, amount of cellular debris, degree of cellular trauma, and the overall ability to make a diagnosis for each sample. Results No significant difference was detected between the 22‐ and 25‐gauge needle samples for cellularity, whereas a significant difference was present for blood contamination, amount of cellular debris, and degree of cellular trauma. The overall ability to make a diagnosis was not significantly affected by the needle gauge. The degree of cellular trauma was significantly increased in intracavitary samples. Conclusions and Clinical Relevance Needle gauge is a contributing factor to FNA sample quality. However, it did not affect the overall ability to make a diagnosis. Samples obtained using 25‐gauge needles resulted in less blood contamination yet increased cellular trauma compared to 22‐gauge needle samples.

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Section: Introductionmentioning

confidence: 99%

Fine‐needle aspiration of cutaneous, subcutaneous, and intracavitary masses in dogs and cats using 22‐ vs 25‐gauge needles

Arai

Rist

Clancey

et al. 2019

Veterinary Clinical Pathol

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“…A retrospective study of 6 dogs showing cardiac tumors demonstrated that ultrasound-guided fine-needle aspiration cytology was able to confirm diagnosis in all cases (Pedro et al, 2016). However, in the present study, this procedure was not performed, due to the inherent risks of the technique and also to the fact that, by the cytology of effusion, the diagnosis was already conclusive.…”

Section: Discussionmentioning

confidence: 55%

Cardiac lymphoma in dogs –

Noronha¹,

Bakiewicz²,

Biondi³

et al. 2019

Braz. J. Vet. Res. Anim. Sci.

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Lymphoma is a very common lymphoid malignancy in dogs, but cardiac involvement is rare. Primary cardiac lymphoma is defined as lymphoma involving the heart, the pericardium, or both, and is classified as extranodal anatomical form. The present report describes the cases of three animals with cardiac lymphoma. All cases presented moderate to severe pericardial effusion and cardiac tamponade. The cytological analysis of the effusion was consistent with the diagnosis of cardiac lymphoma. The anatomopathological evaluation of the tumor extracted from the heart of one of the animals, after euthanasia, was consistent with cardiac lymphoma. The other two animals were treated with Madison-Wisconsin chemotherapy protocol and survived between 6 to 8 months. This report emphasizes the importance of pericardial effusion cytology for the diagnosis, appropriate treatment approach and monitoring of cardiac tumors in dogs and cats.

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“…Fato interessante é a ocorrência da efusão pleural em momento posterior quando comparado à efusão abdominal (de evolução rápida), o que pode ter ocorrido pelo quimiodectoma, já que não se observou HSA em cavidade torácica. O ecocardiograma, não realizado por restrição financeira, poderia ser ferramenta diagnóstica vantajosa, mesmo sem alterações evidenciadas ao ECG, pois poderia permitir avaliar tamanho e localização da neoplasia, além de possibilitar punção guiada e determinar o grau de comprometimento cardíaco existente e o prognóstico [17].…”

Section: Discussionunclassified

Hemangiosarcoma associated with Chemodectoma in an Old Pit Bull Bitch

Tineli

Conte

Strack

et al. 2020

Acta Scientiae. Vet.

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Background: The prevalence of neoplasms in domestic animals has been augmenting over the years. Hemangiosarcoma, which most frequently affects large breed dogs, is a neoplasm with high metastatic power and corresponds to 5% of malignant neoplasms. Chemodectoma, a neoplasm that can have malignant or benign behavior, is uncommon, corresponding to less than 8% of all cardiac tumors, and originates from cardiac chemoreceptor cells and involves mainly the aortic and carotid bodies. The aim of this study is to describe the case of an elderly Pit Bull dog with hepatic hemangiosarcoma and chemodectoma associated with four other different tumors: hemangioma, papilloma, mastocitoma and melanoma.Case: A 14-year-old female Pit Bull, castrated, was presented to Veterinary Clinic of the Federal University of Santa Catarina (UFSC), Curitibanos Campus, Brazil. The owner referred apathy, hyporexia, and increased abdominal volume for two weeks. Physical examination showed emaciation and abdominal effusion. Abdominocentesis was performed, three liters of serosanguineous fluid was drained and a sample was sent for analysis. Complementary tests were requested and showed mild hypoalbuminemia, normocytic normochromic anemia, and lymphopenia. The ultrasound examination revealed thickening of vessels and hepatomegaly, in addition to the presence of an oval structure containing hyperechogenic cavitations. Diagnostic exploratory laparotomy was indicated, but the owner refused. Drug therapy was prescribed in a palliative manner and, during the clinical follow-up period, two abdominocentesis procedures and one thoracentesis procedure were performed, both resulting in simple transudate. Finally, the patient developed severe apathy, edema in all limbs, and died at home. Necroscopic examination was done and revealed hemoperitoneum and hemothorax; several nodules with diverse characteristics in the integument were noted, which were classified by histopathological analysis as follicular cyst, papilloma, cavernous hemangioma, mastocytoma, and melanoma. The histological sections of the liver sample showed hemangiosarcoma and those of the urinary bladder showed hemangiosarcoma metastases. In the heart, a nodule was found at the base of the aorta, which was characterized as chemodectoma. Besides that, there was myxomatous mitral valve degeneration. The necropsy report indicated that the cause of death was hypovolemic shock associated with complications from multiple tumors, particularly hepatic hemangiosarcoma and chemodectoma.Discussion: Hemangiosarcoma is a malignant tumor with invasive behavior. The patient was an elderly Pit Bull dog, a breed not described as being predisposed to this type of tumor. Similarly to other reports in the literature, there was abdominal effusion with rapid and recurrent evolution, progressive weight loss, and metastases in the urinary bladder. It is believed that thoracic effusion, limb edema, and hepatic venous congestion were probably caused by chemodectoma owing to right-sided congestive heart failure. Although not related to the cause of death of this patient, the presence of tumors like papilloma, mastocytoma, melanoma, and hemangioma is noteworthy because the canine had a total of six different types of neoplasms, rarely reported in Pit Bull dogs. This work emphasizes the importance of necroscopic evaluation, which, in this case, was essential for the definitive diagnosis.

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Cytological diagnosis of cardiac masses with ultrasound guided fine needle aspirates

Cited by 17 publications

References 16 publications

Fine‐needle aspiration of cutaneous, subcutaneous, and intracavitary masses in dogs and cats using 22‐ vs 25‐gauge needles

Fine‐needle aspiration of cutaneous, subcutaneous, and intracavitary masses in dogs and cats using 22‐ vs 25‐gauge needles

Cardiac lymphoma in dogs –

Hemangiosarcoma associated with Chemodectoma in an Old Pit Bull Bitch

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