Molluscum contagiosum (MC) is most frequently a self-limiting benign viral skin disease. Transmitted by direct skin contact, it is characterized by flesh-colored, dome-shaped, umbilicated lesions. Diagnosis of MC is often done clinically, but when needed, biopsy can be performed, in which characteristic Henderson-Patterson bodies, representing intracytoplasmic assemblies of the virus, are pathognomonic. Atypical presentations of MC are rare in immunocompetent individuals and are challenging to diagnose. We report a case of giant MC, presenting as an ulcero-proliferative growth, in neck of an 8-month-old female child. Fine-needle aspiration cytology smears revealed characteristic intracytoplasmic molluscum bodies. The diagnosis was subsequently confirmed by histopathology. In this case, cytological examination helped in reaching the correct diagnosis, in a clinically unsuspected case.