Cytology of Pilomatrixoma (Calcifying Epithelioma of Malherbe) in Fine Needle Aspirates

Domański, Henryk; Domanski, Anna M.

doi:10.1159/000332702

Cited by 45 publications

(42 citation statements)

References 8 publications

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“…There was one case of pilomatrixoma, can be differentiated from keratinous cyst by presence of ghost cells and basaloid cells. But some time aspiration cannot represent basaloid cells and mistakenly labelled as epidermal cyst [10,11] In skin lesion one should not forget about parasitic and fungal infection and always take effort in necrotic and fluidy material to find out fungus and parasite. As in our study on cytology examination we found scolices and hooklets of Hydatid cyst, Cysticercosis and hyphae of fungus in cystic lesion.…”

Section: Discussionmentioning

confidence: 99%

Study of Cytodiagnosis of Cutaneous and Subcutaneous Lesions: Experience in a Tertiary Care Hospital

Bode¹

2017

jmscr

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Section: Discussionmentioning

confidence: 99%

Study of Cytodiagnosis of Cutaneous and Subcutaneous Lesions: Experience in a Tertiary Care Hospital

Bode¹

2017

jmscr

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“…As demonstrated by Domanski 25 , the presence of ghost cells in cytological aspirates from pilomatrixomas is rare in alcohol-fixed and abundant in air-dried smears. Consequently, clinicians should make the cytopathologist alert to the potential diagnosis of a pilomatrixoma.…”

Section: Discussionmentioning

confidence: 93%

Pediatric parotideomasseteric pilomatrixoma in children

Salzman

Stárek²,

Faisal³

et al. 2014

Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub

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Aims. To review definitive histological diagnoses of patients with great salivary gland tumors with focus on the relatively high incidence of pediatric pilomatrixomas. The authors focus on clinical investigation, imaging methods and fine needle aspiration cytology of pilomatrixomas. Methods. We treated 12 children with great salivary gland masses aged from 6 months to 18 years from 1995 to 2010. The records of these patients were reviewed to determine sex, age, clinical presentation, and histological findings. Results. Among children having true neoplasms, there was a prevalence of carcinomas (6 out of 9), with low-grade mucoepidermoid and acinic cell carcinomas (two each) as the dominating histopathological diagnosis. There was one adenoid cystic carcinoma and one curious undifferentiated carcinoma in a 6 month old baby. Among all 6 benign lesions, accounting for a half of the total, pilomatrixoma was the most common (2 out of 6) diagnosis, representing 17% (2 out of 12) of all salivary gland lumps and 66% (2 out of 3) of all true benign neoplasms. Conclusions. Pilomatrixoma should be included in the differential diagnosis of pediatric parotideomasseteric lumps. Clinical investigation reveals adherence to the skin but not to the underlying tissue. Clinical assessment and ultrasound guided fine needle aspiration cytology in typical findings strongly support the diagnosis. Cytopathologists must be aware of the preliminary diagnosis of a pilomatrixoma to use proper fixation of the smears. In doubts, frozen biopsy must be sent before parotidectomy is performed.

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“…Fine-needle aspiration may reveal the presence of ghost cells, basaloid cells and calcium deposition in the mass, findings that are diagnostic of pilomatricoma. However, without the presence of ghost cells in the aspirate, the diagnosis may be misleading (19).…”

Section: Discussionmentioning

confidence: 99%