2018
DOI: 10.1002/cncy.22045
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Cytology techniques for minimally invasive molecular autopsies: An opportunity not to be missed

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Cited by 1 publication
(2 citation statements)
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“…Although not ideal, this practice is common in autopsy centres and may reflect a difficulty in using FFPE material when strict protocols for molecular analysis do not exist. This is, therefore, the ideal scenario for cytology, where interference of external contaminants is minimised and nucleic acid quality and purity is usually better 8 …”
Section: Discussionmentioning
confidence: 99%
See 1 more Smart Citation
“…Although not ideal, this practice is common in autopsy centres and may reflect a difficulty in using FFPE material when strict protocols for molecular analysis do not exist. This is, therefore, the ideal scenario for cytology, where interference of external contaminants is minimised and nucleic acid quality and purity is usually better 8 …”
Section: Discussionmentioning
confidence: 99%
“…In this scenario, a viable alternative would be to adopt cytological samples as the standard specimens for molecular processing of autopsy material: it is rapidly collected (scraped or exfoliated), does not go through formaldehyde fixation and paraffin embedding and serves as a fast control of tissue adequacy/tumour content/grade of autolysis 7,8 . In addition, cytology is also a valuable diagnostic tool in autopsies, with good correlation with tissue diagnosis 1 .…”
Section: Introductionmentioning
confidence: 99%