2014
DOI: 10.1007/s00417-014-2782-4
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Cytomegalovirus anterior uveitis: long-term follow-up of immunocompetent patients

Abstract: CMV-associated anterior uveitis has a fairly good long-term visual prognosis. Antiviral therapy can reduce the frequency of relapses, but cataracts and a chronic raise in IOP are frequent complications often requiring a surgical approach.

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Cited by 67 publications
(52 citation statements)
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“…Disease course was characterized as recurrent in nine patients (56.3%) and chronic in seven (43.7%). These findings were generally consistent with those reported by others [5][6][17][18][19][20] and highlight several important facts: First, for reasons that are not entirely clear, CMV-associated anterior uveitis appears to occur far more often in Asians than non-Asians; second, the clinical presentation of CMV-associated anterior uveitis can be quite variable, and is often initially diagnosed as PSS, FHI/FUS, or herpetic anterior uveitis due to either herpes simplex virus (HSV) or varicella zoster virus (VZV) infection; 1,21 and third, both the inflammation and IOP in eyes with CMV-associated uveitis can be quite difficult to control, with many patients requiring long-term topical nonsteroidal anti-inflammatory drugs (NSAIDs) together with topical or systemic ganciclovir therapy. 22 …”
supporting
confidence: 93%
“…Disease course was characterized as recurrent in nine patients (56.3%) and chronic in seven (43.7%). These findings were generally consistent with those reported by others [5][6][17][18][19][20] and highlight several important facts: First, for reasons that are not entirely clear, CMV-associated anterior uveitis appears to occur far more often in Asians than non-Asians; second, the clinical presentation of CMV-associated anterior uveitis can be quite variable, and is often initially diagnosed as PSS, FHI/FUS, or herpetic anterior uveitis due to either herpes simplex virus (HSV) or varicella zoster virus (VZV) infection; 1,21 and third, both the inflammation and IOP in eyes with CMV-associated uveitis can be quite difficult to control, with many patients requiring long-term topical nonsteroidal anti-inflammatory drugs (NSAIDs) together with topical or systemic ganciclovir therapy. 22 …”
supporting
confidence: 93%
“…While clinical findings can be variable, it has been shown to cause a unilateral (occasionally bilateral) anterior chamber inflammation associated with iris sectoral defects, episodes of ocular hypertension, and diffuse fine to medium keratic precipitates, occasionally with focal endotheliitis. [ 2527 ] It can be acute, recurrent, or chronic, and some cases may have been previously characterized as Posner-Schlossman syndrome. This diagnosis can be confirmed with PCR from an aqueous paracentesis.…”
Section: Viral Uveitismentioning
confidence: 99%
“…It can present like Posner-Schlossman syndrome or Fuchs’ heterochromic iridocyclitis and may be associated with acute relapsing or chronic raised intraocular pressure (IOP). 118 …”
Section: Infectious Uveitidesmentioning
confidence: 99%