Cytomegalovirus Infection of the Colon Presenting as a Mass-Like Lesion

Abstract

Cytomegalovirus (CMV) is responsible for the most common opportunistic infections in patients with acquired immunodeficiency syndrome (AIDS). The colon is a common site for these infections in patients positive for human immunodeficiency virus. CMV rarely presents as an intraluminal inflammatory mass in the colon. Here we report the case of a CMV infection presenting as a mass-like lesion in an AIDS patient. The clinical diagnosis of CMV infection is largely based on the characteristic endoscopic appearance. Endoscopic procedures are encouraged early in the course of CMV infection in immunocompromised patients. CMV pseudotumors along with malignancy should be part of the endoscopic evaluation in patients with AIDS.

Spindle Cell Pseudotumor Mimicking Malignancy in an Immunocompetent Patient with a Left Ventricular Assist Device

“…Immunohistochemical markers, such as receptor tyrosine kinase (c-kit) inhibitors, platelet-derived growth factor receptor α, CD34, and SMA, are often necessary for accurate diagnosis. 10 The histopathologic hallmark of CMV infection is the central density of eosinophilic inclusions with a surrounding halo, commonly known as the “owl’s eye.” 1 , 9 , 11 …”

Sevelamer-Induced Colitis Presenting as a Pseudotumor

“…Mass formation in the setting of colitis has been described in the setting of ischemic colitis 3 and cytomegalovirus colitis. 4 Mass formation in the setting of colitis has been attributed to submucosal hemorrhage. 3 As with most cases of medication-induced adverse effects, stopping the offending agent is a good first step in management.…”