Cytomegalovirus primoinfection in inflammatory bowel disease

Torres, Paola; Lobatón, Triana; Cañete, Fiorella; Clos, Ariadna; Mañosa, Míriam; Cabré, Eduard; Domènech, Eugeni

doi:10.1016/j.gastre.2018.06.001

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Treatment -Feasible or Futile?1

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Cited by 2 publications

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“…Case reports have described severe disseminated CMV infection, generally primary CMV infection. [147] These cases are characterized by a mononucleosis-like syndrome or CMV syndrome [positive serum PCR with fever, malaise, leukopenia, low platelet count, and elevated liver enzymes]. [148].…”

Section: Accepted Manuscriptmentioning

confidence: 99%

ECCO Guidelines on the Prevention, Diagnosis, and Management of Infections in Inflammatory Bowel Disease

Kucharzik

Ellul

Greuter

et al. 2021

Journal of Crohn's and Colitis

280

235

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Section: Accepted Manuscriptmentioning

confidence: 99%

ECCO Guidelines on the Prevention, Diagnosis, and Management of Infections in Inflammatory Bowel Disease

Kucharzik

Ellul

Greuter

et al. 2021

Journal of Crohn's and Colitis

280

235

View full text Add to dashboard Cite

“…Case reports have described primary disseminated CMV infection, characterised by a mononucleosis-like syndrome with positive serum CMV DNA PCR, fever, leukopenia, thrombocytopenia, and transaminitis, in UC patients receiving immunosuppressants (Torres et al, 2018;Fakhreddine et al, 2019). In such cases, discontinuation of immunosuppressive therapy is recommended.…”

Section: Treatment -Feasible or Futile?mentioning

confidence: 99%

A quick guide to diagnosis and treatment of cytomegalovirus infection in the gut: current dilemmas

Drjagunovs

Laivacuma

Zeltiņa

et al. 2022

Proceedings of the Latvian Academy of Sciences. Section B. Natural, Exact, and Applied Sciences.

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Cytomegalovirus is a ubiquitous herpesvirus, which, after often asymptomatic primary infection, establishes a life-long latency in different organs, including gut. As there is a close synergistic relationship between mucosal inflammation and viral expression, particularly in patients suffering from inflammatory bowel disease, it is often challenging to distinguish subclinical cytomegalovirus replication from cytomegalovirus-mediated colitis. The outcome for patients with cytomegalovirus reactivation appears to be worse than that for patients without reactivation, but the true role of cytomegalovirus is not entirely clear, as is the dilemma whether specific treatment with antivirals alters the course of inflammatory bowel disease. This review focuses on gastrointestinal tract cytomegalovirus disease, with special emphasis on diagnostic and treatment considerations of cytomegalovirus colitis in patients with inflammatory bowel disease.

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Cytomegalovirus primoinfection in inflammatory bowel disease

Cited by 2 publications

References 9 publications

ECCO Guidelines on the Prevention, Diagnosis, and Management of Infections in Inflammatory Bowel Disease

ECCO Guidelines on the Prevention, Diagnosis, and Management of Infections in Inflammatory Bowel Disease

A quick guide to diagnosis and treatment of cytomegalovirus infection in the gut: current dilemmas

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