Cytomegalovirus retinitis in Good Syndrome

Pulmonary Manifestations of Predominantly Antibody Deficiencies

“…Particularly, persistent infection (pneumonia) following thymectomy might warrant that your patient is very likely to have GS [101][102][103][104][105]. Overall, respiratory manifestations in association with GS include recurrent sinopulmonary infections (sinusitis, rhinosinusitis, otitis media, and pneumonia) [106][107][108][109][110][111][112][113][114] with bacterial (especially with encapsulated bacteria including Haemophilus influenzae), fungal (aspergillus and P. carinii), and viral (CMV and HSV) pathogens [115][116][117][118][119][120][121], tracheobronchitis [118], diffuse panbronchiolitis [122][123][124], granulomatous lung disease [125], and pulmonary nodules [123]. As for patients with other forms of agammaglobulinemia, patients with GS remain dependent on immunoglobulin replacement therapy.…”