Cytomorphological Study of Oral Exfoliated Cells in Type II Diabetes Mellitus Patients

Abstract

Introduction: Diabetes mellitus (DM) is one of the most common endocrine metabolic disorders and its prevalence has been increasing worldwide. It is a third leading cause of mortality and morbidity in the world. Diabetes affects several organs including the oral cavity. The oral complications of uncontrolled DM can include xerostomia, infection, poor healing, increased incidence and severity of caries, candidiasis, gingivitis, periodontal disease, periapical abscesses, and burning mouth syndrome. Early diagnosis of the DM is an important aspect of health care. Exfoliative cytology is considered a moderate, straightforward, and noninvasive diagnostic marker for DM. The purpose of this study is to demonstrate cytologic changes of the exfoliated oral mucosal cells of diabetic patients using hematoxylin and eosin (H&E) staining technique to establish its role as diagnostic criteria.