Cytotoxic and antioxidant constituents from Garcinia subelliptica

Quantitative assessment of bioactive compounds and the antioxidant activity of 15 jujube cultivars

“…A negative correlation between the total triterpenes content and the ABTSÁ-scavenging activity (R 2 = À0.374, p < 0.05) was observed in the paper and also by other studies (Feng et al, 2014). The explanation behind this result is still unclear, as triterpenes have been demonstrated to have antioxidant capacity (Lin et al, 2012;Liu et al, 2010).…”

A novel natural tautomeric pair of garcinielliptone FC suppressed nuclear factor κB and induced apoptosis in human colorectal cancer cells

“…Our unpublished data indicated that time-and dosage-related induction of apoptosis was observed in response to GFC, which was associated with activation of caspases and dysfunction of mitochondria. Induction of apoptosis in response to GFC was also observed in our previous reports using human breast cancer MCF-7 cells and human bladder cancer NTUB1 cells (Lin et al, 2012). Recently, a connection between inflammation and carcinogenesis has been evidenced.…”

Celecoxib-Induced Cytotoxic Effect Is Potentiated by Inhibition of Autophagy in Human Urothelial Carcinoma Cells

“…NTUB1 cell line, kindly provided from Dr. Yeong-Shiau Pu (Department of Urology, National Taiwan University Hospital, Taipei, Taiwan), was derived from the surgical specimen of a 70-year-old female patient with high grade transitional bladder cell carcinoma and were reported to be tumorigenic in a xenograft model [16], [25], [26], [27], [28], [29], [30], [31], [32]. T24 cell line, obtained from the Bioresource Collection and Research Center (BCRC, Hsinchu, Taiwan), was derived from a highly malignant grade III human urinary bladder carcinoma [33].…”