Cytotoxic Anthraquinones from the Aerial Parts of Acalypha australis

Ma, Qinge; Wei, Rongrui; Liu, Wenmin; Sang, Zhipei; Guo, Xiuhuan

doi:10.1007/s10600-017-2165-2

Cited by 8 publications

(1 citation statement)

References 11 publications

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“…This is a strong hint for the presence of phenolic hydroxyl groups in 1, which was not unexpected for an EA derivative. In agreement with data from the literature [37][38][39], the presence of a benzene ring, conjugated carbonyl groups, and phenolic hydroxyl groups can be assumed based on the presence of the maxima at 232 (4.10), 290 (3.95), and 407 (3.96) nm in the UV-Vis absorption spectra of 1 (Figure S9-1).…”

Section: Structure Elucidationsupporting

confidence: 88%

Challenging Structure Elucidation of Lumnitzeralactone, an Ellagic Acid Derivative from the Mangrove Lumnitzera racemosa

et al. 2023

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The previously undescribed natural product lumnitzeralactone (1), which represents a derivative of ellagic acid, was isolated from the anti-bacterial extract of the Indonesian mangrove species Lumnitzera racemosa Willd. The structure of lumnitzeralactone (1), a proton-deficient and highly challenging condensed aromatic ring system, was unambiguously elucidated by extensive spectroscopic analyses involving high-resolution mass spectrometry (HRMS), 1D 1H and 13C nuclear magnetic resonance spectroscopy (NMR), and 2D NMR (including 1,1-ADEQUATE and 1,n-ADEQUATE). Determination of the structure was supported by computer-assisted structure elucidation (CASE system applying ACD-SE), density functional theory (DFT) calculations, and a two-step chemical synthesis. Possible biosynthetic pathways involving mangrove-associated fungi have been suggested.

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Section: Structure Elucidationsupporting

confidence: 88%

Challenging Structure Elucidation of Lumnitzeralactone, an Ellagic Acid Derivative from the Mangrove Lumnitzera racemosa

et al. 2023

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Plant anthraquinones: Classification, distribution, biosynthesis, and regulation

Wang

Jia

Hua

et al. 2023

Journal Cellular Physiology

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Anthraquinones are polycyclic compounds with an unsaturated diketone structure (quinoid moiety). As important secondary metabolites of plants, anthraquinones play an important role in the response of many biological processes and environmental factors. Anthraquinones are common in the human diet and have a variety of biological activities including anticancer, antibacterial, and antioxidant activities that reduce disease risk. The biological activity of anthraquinones depends on the substitution pattern of their hydroxyl groups on the anthraquinone ring structure. However, there is still a lack of systematic summary on the distribution, classification, and biosynthesis of plant anthraquinones. Therefore, this paper systematically reviews the research progress of the distribution, classification, biosynthesis, and regulation of plant anthraquinones. Additionally, we discuss future opportunities in anthraquinone research, including biotechnology, therapeutic products, and dietary anthraquinones.

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Three New Anthraquinones from Aerial Parts of Paederia scandens

Zhang

Zhou

et al. 2018

Chem Nat Compd

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Cytotoxic Anthraquinones from the Aerial Parts of Acalypha australis

Cited by 8 publications

References 11 publications

Challenging Structure Elucidation of Lumnitzeralactone, an Ellagic Acid Derivative from the Mangrove Lumnitzera racemosa

Challenging Structure Elucidation of Lumnitzeralactone, an Ellagic Acid Derivative from the Mangrove Lumnitzera racemosa

Plant anthraquinones: Classification, distribution, biosynthesis, and regulation

Three New Anthraquinones from Aerial Parts of Paederia scandens

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