Cytotoxic compounds from invasive giant salvinia (Salvinia molesta) against human tumor cells

Li, Shiyou; Wang, Ping; Deng, Guo-Min; Wei, Yuan; Su, Zushang

doi:10.1016/j.bmcl.2013.10.040

Cited by 35 publications

(23 citation statements)

References 44 publications

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“…Indicatively, ferruginol (identified by GC-MS) is an abietane diterpene that along with several of its derivatives, in ethanolic extracts displayed cytotoxic activity against human tumor cells [62]. …”

Section: Discussionmentioning

confidence: 99%

Revisiting Greek Propolis: Chromatographic Analysis and Antioxidant Activity Study

et al. 2017

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Propolis is a bee product that has been extensively used in alternative medicine and recently has gained interest on a global scale as an essential ingredient of healthy foods and cosmetics. Propolis is also considered to improve human health and to prevent diseases such as inflammation, heart disease, diabetes and even cancer. However, the claimed effects are anticipated to be correlated to its chemical composition. Since propolis is a natural product, its composition is consequently expected to be variable depending on the local flora alignment. In this work, we present the development of a novel HPLC-PDA-ESI/MS targeted method, used to identify and quantify 59 phenolic compounds in Greek propolis hydroalcoholic extracts. Amongst them, nine phenolic compounds are herein reported for the first time in Greek propolis. Alongside GC-MS complementary analysis was employed, unveiling eight additional newly reported compounds. The antioxidant activity study of the propolis samples verified the potential of these extracts to effectively scavenge radicals, with the extract of Imathia region exhibiting comparable antioxidant activity to that of quercetin.

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Section: Discussionmentioning

confidence: 99%

Revisiting Greek Propolis: Chromatographic Analysis and Antioxidant Activity Study

et al. 2017

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“…Hence, herbal immunostimulants can be an effective alternative strategy in lieu of antibiotics and chemotherapies in marine disease management [15]. Ethanolic extract of S. molesta, an abundantly available freshwater weed, was proven for its cytotoxic activity against human non-small cell lung cells but not toxic to normal human lung fibroblasts cells [8]. The previous studies also have proven that S. molesta has a potent antioxidant and antibacterial activity against A. hydrophila and is rich in significant phytochemicals [16].…”

Section: Discussionmentioning

confidence: 99%

“…The plant could double its biomass in 2-3 days under favorable conditions and can stay functional even at dry conditions [7]. The potentially of S. molesta to accumulate certain metals and effluent treatment was recently studied and proven, whereas the medical or pharmaceutical potential of giant S. molesta remains still underexplored [8]. Hence, the present study was focused on screening the immunostimulant activity of S. molesta extract in freshwater crab Oziotelphusa senex senex challenged with Aeromonas hydrophila.…”

Section: Introductionmentioning

confidence: 99%

Immune Protection of Salvinia Molesta D.S. Mitchell in Freshwater Crab Oziotelphusa Senex Senex Bacterially Challenged With Aeromonas Hydrophila

Tg¹,

Jayanthi²,

Mg³

et al. 2017

Asian J Pharm Clin Res

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Objective: This is aimed to study the immune protection parameters of freshwater weed Salvinia molesta in bacterially challenged freshwater crab Oziotelphusa senex senex. Methods:In this present study, ethanolic extract of freshwater weed S. molesta was tested for its ability to induce immunity in bacterial challenged freshwater crab O. senex senex. Male and female crabs were challenged with Aeromonas hydrophila in relevant concentrations. The treated groups were allowed to withstand for 96 hrs. After relevant incubation time, the hemolymph of the treated crabs was subjected for various hematological, biochemical, and immunological assays. Results:Total hemocyte count increased on infection at 96 hrs, whereas significantly reduced on treatment with S. molesta at 96 hrs. All the three cell types of differential hemocytes showed significant positive changes on treatment. Levels of prophenoloxidase decreased significantly on infection and showed a significant increase in treated groups at 96 hrs of treatment. Conclusion:The present study elucidated the medicinal and pharmaceutical role of S. molesta weed which is been subjected to eradication in the recent days. Thus, the plant source can be utilized as an immunomodulatory agent and a better alternative to treat aquatic diseases.

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“…Mechanical removal of salvinia and use of weedicide have recorded even lesser success in controlling its spread. Attempts to utilize salvinia for the generation of compost, green manure or mulch (Raju and Gangwar 2004;Arthur et al 2007;Dorahy et al 2009), as fodder (King et al 2004;Leterme et al 2010), as a source of biogas (Abbasi et al 1990;Abbasi and Nipaney 1991;Abbasi et al 1992a, b;Abbasi and Abbasi 2010;Ganesh et al 2005), or for making drugs (Chantiratikul et al 2009;Choudhary et al 2008;Li et al 2013;Tauseef et al 2013), have all proved uneconomical. Thus, finding a sustainable, ecologically sound, and inexpensive way with which salvinia biomass can be utilized on the scales it is generated appears to be the only recourse which can make it profitable to regularly harvest the weed, thereby keeping a check on its alarming growth.…”

Section: Introductionmentioning

confidence: 99%

Enhancement in the productivity of ladies finger (Abelmoschus esculentus) with concomitant pest control by the vermicompost of the weed salvinia (Salvinia molesta, Mitchell)

Hussain

Abbasi

2017

Int J Recycl Org Waste Agricult

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Purpose In a novel attempt, vermicompost derived from an intransigent and noxious weed salvinia was assessed for its fertilizer value and pest repellent properties. Methods In outdoor experiments which simulated the way vegetables are cultivated by farmers, ladies finger (Abelmoschus esculentus) seeds were germinated and grown in soil supplemented with salvinia vermicompost at four levels: 0 (V 0 ), 2.5 (V 1 ), 3.75 (V 2 ) and 5 (V 3 ) t/ha. Besides assessing germination success and subsequent growth, yield, and biochemical content of the plants, the impact of pest attacks on them was also studied. Results Salvinia vermicompost significantly enhanced germination success, growth, and yield of the plants. Maximum growth in terms of shoot length (96.2 cm), root length (48.2 cm), shoot and root dry weight (23.31, 7.96 g), stem diameter (14.04 mm), and number of leaves and branches (26.8, 4.8) was recorded in V 4 (5t/ha). Likewise, the mineral and biochemical content in vermicompost-treated plants was significantly higher than in the controls. The vermicompost also induced resistance in plants against pests and disease. Compared to the controls, vermicompost had reduced the fruit borer infection by 65, 78 and 82% in V 1 , V 2 and V 3 , respectively. Conclusion The toxicity of salvinia is largely eliminated when it is vermicomposted, and the product acquires the qualities of a good organic fertilizer. The present work can potentially lead to the development of an inexpensive, sustainable and eco-friendly method of utilizing billions of tons of phytomass that is generated annually by salvinia, and which presently goes to waste.

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Cytotoxic compounds from invasive giant salvinia (Salvinia molesta) against human tumor cells

Cited by 35 publications

References 44 publications

Revisiting Greek Propolis: Chromatographic Analysis and Antioxidant Activity Study

Revisiting Greek Propolis: Chromatographic Analysis and Antioxidant Activity Study

Immune Protection of Salvinia Molesta D.S. Mitchell in Freshwater Crab Oziotelphusa Senex Senex Bacterially Challenged With Aeromonas Hydrophila

Enhancement in the productivity of ladies finger (Abelmoschus esculentus) with concomitant pest control by the vermicompost of the weed salvinia (Salvinia molesta, Mitchell)

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