Cytotoxic Cytochalasins from Marine-Derived Fungus Arthrinium arundinis

Wang, Junfeng; Wang, Zhen; Zhang, Ju; Wan, Junting; Liao, Shengrong; Lin, Xiuping; Zhang, Tianyu; Zhou, Xuefeng; Chen, Hao; Tu, Zhengchao; Liu, Yonghong

doi:10.1055/s-0034-1383403

Cited by 49 publications

(21 citation statements)

References 23 publications

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“…were also retrieved in both sampling sites. These genera are frequently isolated from terrestrial environments [70, 71] but include species that colonize marine substrata, saline and hypersaline environments [12, 41, 47–49, 72, 73]. …”

Section: Discussionmentioning

confidence: 99%

The culturable mycobiota of Flabellia petiolata: First survey of marine fungi associated to a Mediterranean green alga

et al. 2017

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Algae-inhabiting marine fungi represent a taxonomically and ecologically interesting group of microorganisms still largely neglected, especially in temperate regions. The aim of this study was to isolate and to identify the culturable mycobiota associated with Flabellia petiolata, a green alga frequently retrieved in the Mediterranean basin. Twenty algal thalli were collected from two different sampling sites in the Mediterranean Sea (Elba Island, Italy). A polyphasic approach showed the presence of a relevant alga-associated mycobiota with 64 taxa identified. The fungal isolates belonged mainly to Ascomycota (61 taxa), while only three Basidiomycota were detected. The phylogenetic position of sterile mycelia and cryptic taxa, inferred on the basis of LSU partial region, highlighted the presence of putative new phylogenetic lineages within Dothideomycetes and Sordariomycetes. This work represents the first quali-quantitative analysis of the culturable mycobiota associated to a green alga in the Mediterranean Sea.

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Section: Discussionmentioning

confidence: 99%

The culturable mycobiota of Flabellia petiolata: First survey of marine fungi associated to a Mediterranean green alga

et al. 2017

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“…Among the isolated fungal metabolites, compounds 2 , 3 and 7 showed cytotoxic activity with IC 50 ranges of 50.6–193.3 µM, but all compounds ( 1 – 7 ) did not inhibit caspase-3 activity. New bioactive secondary metabolites with diverse chemical skeletons have recently been isolated from marine fungi [ 30 , 31 , 32 ]. The present work underscores that marine fungi are important sources of bioactive natural products.…”

Section: Discussionmentioning

confidence: 99%

Drimane Sesquiterpene-Conjugated Amino Acids from a Marine Isolate of the Fungus Talaromyces minioluteus (Penicillium Minioluteum)

et al. 2015

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Four new sesquiterpene lactones (3, 4, 6 and 7) and three known compounds, purpuride (1), berkedrimane B (2) and purpuride B (5), were isolated from the marine fungus, Talaromyces minioluteus (Penicillium minioluteum). New compounds were drimane sesquiterpenes conjugated with N-acetyl-l-valine, and their structures were elucidated by analysis of spectroscopic data, as well as by single crystal X-ray analysis. The isolated compounds could not inhibit the apoptosis-regulating enzyme, caspase-3, while three of the compounds (2, 3 and 7) exhibited weak cytotoxic activity.

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“…Studies of fungi continue to be on the rise with 371 172 Citromycetin analogue 184 was obtained from an Ascomyta sp., 174 while as usual, the genus Aspergillus has been well studied. Of particular note was a continuing study into the biosynthesis of the prenylated indole alkaloids notoamides, 175 stephacidins 176 and versicolamide B.…”

Section: Marine-sourced Fungi (Excluding From Mangroves)mentioning

confidence: 99%

Marine natural products

et al. 2017

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Covering: 2015. Previous review: Nat. Prod. Rep., 2016, 33, 382-431This review covers the literature published in 2015 for marine natural products (MNPs), with 1220 citations (792 for the period January to December 2015) referring to compounds isolated from marine microorganisms and phytoplankton, green, brown and red algae, sponges, cnidarians, bryozoans, molluscs, tunicates, echinoderms, mangroves and other intertidal plants and microorganisms. The emphasis is on new compounds (1340 in 429 papers for 2015), together with the relevant biological activities, source organisms and country of origin. Reviews, biosynthetic studies, first syntheses, and syntheses that lead to the revision of structures or stereochemistries, have been included.

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Cytotoxic Cytochalasins from Marine-Derived Fungus Arthrinium arundinis

Cited by 49 publications

References 23 publications

The culturable mycobiota of Flabellia petiolata: First survey of marine fungi associated to a Mediterranean green alga

The culturable mycobiota of Flabellia petiolata: First survey of marine fungi associated to a Mediterranean green alga

Drimane Sesquiterpene-Conjugated Amino Acids from a Marine Isolate of the Fungus Talaromyces minioluteus (Penicillium Minioluteum)

Marine natural products

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