Cytotoxic effects of novel solvothermal synthesised Ag-doped PEGylated WO3 sheet-like nanocomposites on MCF-7 human breast cancer cells

Ngigi, Eric M.; George, Blassan P.; Abrahamse, Heidi; Nomngongo, Philiswa N.; Ngila, Jane Catherine

doi:10.1007/s11051-020-04929-0

Cited by 8 publications

(3 citation statements)

References 78 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…When doped into PEGylated WO 3 nanocomposites, the new system seems to suggest that doping may be beneficial for enhancing cytotoxicity. [ 127 ] These studies have shown that TNMs may play a certain role in CHT because of their intrinsic characteristics rather than their role as carriers.…”

Section: Research Hotspots Of Tnms In the Biomedical Fieldmentioning

confidence: 99%

Tungsten‐based Nanomaterials in the Biomedical Field: A Bibliometric Analysis of Research Progress and Prospects

Wang

Pan

et al. 2022

Advanced Materials

View full text Add to dashboard Cite

Tungsten‐based nanomaterials (TNMs) with diverse nanostructures and unique physicochemical properties have been widely applied in the biomedical field. Although various reviews have described the application of TNMs in specific biomedical fields, there are still no comprehensive studies that summarize and analyze research trends of the field as a whole. To identify and further promote the development of biomedical TNMs, a bibliometric analysis method is used to analyze all relevant literature on this topic. First, general bibliometric distributions of the dataset by year, country, institute, referenced source, and research hotspots are recognized. Next, a comprehensive review of the subjectively recognized research hotspots in various biomedical fields, including biological sensing, anticancer treatments, antibacterials, and toxicity evaluation, is provided. Finally, the prospects and challenges of TNMs are discussed to provide a new perspective for further promoting their development in biomedical research.

show abstract

Section: Research Hotspots Of Tnms In the Biomedical Fieldmentioning

confidence: 99%

Tungsten‐based Nanomaterials in the Biomedical Field: A Bibliometric Analysis of Research Progress and Prospects

Wang

Pan

et al. 2022

Advanced Materials

View full text Add to dashboard Cite

show abstract

“…Various nanostructures have been used for biomedical applications. Among all nanomaterials include those made of ZnO 1 , CuO, 2 Fe 2 O 3 , 3 V 2 O 5 , 4 MoO 3 , 5 and WO 3 , 6 among others. In comparison to other metal oxide nanostructures mentioned, only limited research has been done on vanadium oxide (V 2 O 5 ) in biomedical applications.…”

Section: ■ Introductionmentioning

confidence: 99%

“…Various nanostructures have been used for biomedical applications. Among all nanomaterials include those made of ZnO, CuO, Fe 2 O 3 , V 2 O 5 , MoO 3 , and WO 3 , among others. In comparison to other metal oxide nanostructures mentioned, only limited research has been done on vanadium oxide (V 2 O 5 ) in biomedical applications. − A wide range of cutting-edge biomedical applications has made use of the special qualities of metal oxide nanostructures, including drug delivery, in vitro and in vivo bioimaging, biosensing, cancer therapy, diagnostics, and photoinduced therapy .…”

Section: Introductionmentioning

confidence: 99%

Nanomaterials Based Multifunctional Bioactivities of V₂O₅ and Mesoporous Carbon@V₂O₅ Composite: Preparation and Characterization

Bhosale,

Dhavale

et al. 2024

Langmuir

View full text Add to dashboard Cite

Nanocarriers have attracted considerable interest due to their prospective applications in the delivery of anticancer medications and their distinct bioactivities. Biogenic nanostructures can be effective nanocarriers for delivering drugs as a consequence of sustainable and biodegradable biomassderived nanostructures that perform specific functions. In this case, a vanadium oxide (V 2 O 5 ) and mesoporous carbon@V 2 O 5 (C@V) composite was developed as a possible drug delivery system, and its bioactivities, including antioxidant, antibacterial, and anticancer, were investigated. Doxorubicin (DOX), an anticancer drug, was introduced to the nanoparticles, and the loading and release investigation was conducted. Strong interfacial interactions between mesoporous carbon (MC) and V 2 O 5 nanostructures have been found to improve performance in drug loading and release studies and bioactivities. After incubation, the potent anticancer effectiveness was seen based on C@V nanocomposite. This sample was also utilized to research potential biomedical uses as an antioxidant, antibacterial, and anticancer. The most effective antioxidant, the C@V sample (61.2%), exhibited a higher antioxidant activity than the V-2 sample (44.61%). The C@V sample ultimately attained a high DOX loading efficacy of 88%, in comparison to a pure V 2 O 5 sample (V-2) loading efficacy of 80%. Due to the combination of mesoporous carbon and V 2 O 5 , which increases specific surface area and surface sites of action as well as the morphology, it proved that the mesoporous carbon@V 2 O 5 composite (C@V) sample demonstrated greater efficacy.

show abstract

Advanced functional polymer materials for biomedical applications

Elsayed,

Teow

2024

J of Applied Polymer Sci

View full text Add to dashboard Cite

Polymer structures are essential in biomedical applications due to their biocompatibility, biodegradability, and ability to form intricate structures on micro‐ to nanometer scales. This review, emphasizing electrospinning and phase inversion techniques, examines the fabrication strategies and chemical design of polymer structures for biomedical use. Electrospinning, particularly needleless electrospinning, produces nanofibres with high porosity and flexibility and is widely applied in tissue engineering and drug delivery. Phase inversion, including thermal, nonsolvent‐, vapor‐ and evaporation‐induced phase separation, allows precise control over polymer properties but faces challenges in terms of cooling rates and solvent characteristics. Chemical design through doping, functionalization, cross‐linking and copolymerization enhances the biocompatibility, biodegradability and mechanical properties of polymers, facilitating advanced applications in drug delivery, tissue scaffolding and biosensors. Advanced functional polymers are revolutionizing biomedical fields, offering innovative solutions for therapeutic medicine delivery, disease detection, diagnostics, and regenerative medicine. Despite remarkable progress, challenges, such as scalability, cost‐effectiveness, and environmental impact, persist. This review underscores the transformative potential of advanced polymer materials in medical treatments and advocates for continuous research and interdisciplinary collaboration to overcome existing challenges and fully exploit the capabilities of these materials in improving patient care and medical outcomes. Future perspectives highlight enhancing precision control mechanisms, integrating phase inversion with other techniques and developing large‐scale production methods to advance the field further.

show abstract

Cytotoxic effects of novel solvothermal synthesised Ag-doped PEGylated WO3 sheet-like nanocomposites on MCF-7 human breast cancer cells

Cited by 8 publications

References 78 publications

Tungsten‐based Nanomaterials in the Biomedical Field: A Bibliometric Analysis of Research Progress and Prospects

Tungsten‐based Nanomaterials in the Biomedical Field: A Bibliometric Analysis of Research Progress and Prospects

Nanomaterials Based Multifunctional Bioactivities of V₂O₅ and Mesoporous Carbon@V₂O₅ Composite: Preparation and Characterization

Advanced functional polymer materials for biomedical applications

Contact Info

Product

Resources

About

Cytotoxic effects of novel solvothermal synthesised Ag-doped PEGylated WO3 sheet-like nanocomposites on MCF-7 human breast cancer cells

Cited by 8 publications

References 78 publications

Tungsten‐based Nanomaterials in the Biomedical Field: A Bibliometric Analysis of Research Progress and Prospects

Tungsten‐based Nanomaterials in the Biomedical Field: A Bibliometric Analysis of Research Progress and Prospects

Nanomaterials Based Multifunctional Bioactivities of V2O5 and Mesoporous Carbon@V2O5 Composite: Preparation and Characterization

Advanced functional polymer materials for biomedical applications

Contact Info

Product

Resources

About

Nanomaterials Based Multifunctional Bioactivities of V₂O₅ and Mesoporous Carbon@V₂O₅ Composite: Preparation and Characterization