Cytotoxic cis-ruthenium(iii) bis(amidine) complexes

Abstract

In chemotherapy, the search for ruthenium compounds as alternatives to platinum compounds is proposed because of their unique properties. However, the geometry effect of ruthenium complexes is sparely investigated. In...

A new Cu(ii) complex derived from the reaction between tris(2-aminoethyl)amine and Cu(i)-activated acetonitrile with potent anticancer activity against some cell lines and high affinity for the essential proteins of SARS-CoV-2

“…9 In particular, the anticancer activities of amidines and their complexes are of great interest to researchers. 10–12 In contrast, the study of the antiviral activity of amidines has only just begun. 13,14 Due to the current corona virus epidemic, many studies have been conducted recently on the anti-COVID-19 efficacy of amidines such as Cl-amidine, F-amidine and BB-Cl-amidine, as protein arginine deiminase (PAD) inhibitors.…”