Cytotoxicity and antimicrobial activity of plants from New Zealand's subantarctic islands

Lorimer, Stephen D.; Barns, G.; Evans, A. C.; Foster, Lysa M.; May, Barnaby C. H.; Perry, Nigel B.; Tangney, Raymond S.

doi:10.1016/s0944-7113(96)80077-8

Cited by 29 publications

(34 citation statements)

References 17 publications

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“…Ertz et al (2005) and Hafellner & Mayrhofer (2007) briefly discuss biogeographical elements in New Zealand's lichenicolous fungal mycobiota, which includes bipolar, endemic, cosmopolitan, autralasian, austral, and pantropical distribution patterns. Lorimer et al (1996), Walker & Lintott (1997), and Perry et al (1999).…”

Section: New Zealandmentioning

confidence: 99%

Austral lichenology: 1690–2008

Galloway¹

2008

New Zealand Journal of Botany

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This review summarises lichen work in the temperate Southern Hemisphere. A brief historical overview of austral lichenology is presented from the earliest European voyages of discovery up to the present day. Current knowledge is outlined for Australia, New Zealand, South Africa, southern South America, the Southern Subpolar islands, and Antarctica. Biogeographical patterns, and the importance of lichens in nutrient cycling, habitat restoration, and monitoring of global change, are also discussed from an austral perspective.

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Section: New Zealandmentioning

confidence: 99%

Austral lichenology: 1690–2008

Galloway¹

2008

New Zealand Journal of Botany

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“…In the light of these results, water has proved to be a natural solvent that can be used in the prevention of dermatosis, although, with the exception of both the above-mentioned research groups, lichen compounds extracted by water to inhibit dermatophytes has yet to be confirmed. Among the secondary lichen metabolites, the highest fungicidal activity was demonstrated by a chloroform solution of 2-hydroxy-4-methoxy-3,6-dimethylbenzoic Lorimer et al 1996;Perry et al 1999), as well as Usnea (Lorimer et al 1996;Perry et al 1999;Schmeda-Hirschmann et al 2008). The high activity of compounds extracted by methanol from P. glauca (36 mm IZ) against T. rubrum ) has been detected, in addition to those extracted by ethanol and n-hexane from R. farinacea (Esimone and Adikwu 1999) and by methanol from R. polymorpha ) and X. pulla .…”

Section: Discussionmentioning

confidence: 99%

“…‡Fungicidal action. ethanol-extracted compounds from numerous lichen species (see Table 6; Lorimer et al 1996;Perry et al 1999). Extracts from many other species, mostly macrolichens, were found to be inactive against this dermatophyte (Perry et al 1999;Aslan et al 2006;Gulluce et al 2006;Yucel et al 2007).…”

Section: Cladonia Verticillarismentioning

confidence: 99%

Antifungal activity of lichen compounds against dermatophytes: a review

Furmanek

Czarnota

Seaward

2019

J of Applied Microbiology

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Summary The growth rate inhibition of dermatophytes by compounds extracted by acetone, ethanol, methanol and water derived from representatives of several lichen genera (e.g. Caloplaca, Everniastrum, Heterodermia, Hypotrachyna, Platismatia and Ramalina) were compared on the basis of a worldwide review of published research. The examined dermatophytes included Epidermophyton floccosum, Microsporum audouinii, M. canis, M. gypseum, M. nanum, Trichophyton longifusus, T. mentagrophytes, T. rubrum, T. tonsurans and T. violaceum. The influence of selected secondary lichen compounds, for example, usnic acid, on the growth rates of these dermatophytes was also reviewed. The measurement of inhibition by lichen compounds was performed by several methods, but mostly those employing disc diffusion, broth dilution and agar dilution. The fungicidal activity of water‐extracted compounds from Heterodermia leucomela and Hypotrachyna cirrhata and of methanol‐extracted compounds from Evernia divaricata and Ramalina pollinaria, as well as protolichesterinic and 2‐hydroxy‐4‐methoxy‐3,6‐dimethylbenzoic acids, are distinguished.

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“…Disease incidence was measured relative to untreated control plants at 24-h post inoculation and, in some tests, at 96 h ( Table 3). The C. albicans assay has been described previously (12).…”

Section: General Experimental Proceduresmentioning

confidence: 99%

Fungicidal Sesquiterpene Dialdehyde Cinnamates from Pseudowintera axillaris

Brennan

Larsen

Lorimer

et al. 2005

J. Agric. Food Chem.

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Bioactivity-directed separation of a foliage extract from the New Zealand shrub Pseudowintera axillaris led to a compound with fungicidal activity against the plant pathogen Phytophthora infestans. This was identified as a new sesquiterpene dialdehyde cinnamate named paxidal. Two 6-hydroxy derivatives were present at lower levels in the extract. A further nine derivatives were synthesized from these natural products for a structure-activity study against a range of important food crop pathogens. The cinnamate group was important for fungicidal effects, and protection of the dialdehyde as a dimethyl acetal gave more potent, broader spectrum activity.

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Cytotoxicity and antimicrobial activity of plants from New Zealand's subantarctic islands

Cited by 29 publications

References 17 publications

Austral lichenology: 1690–2008

Austral lichenology: 1690–2008

Antifungal activity of lichen compounds against dermatophytes: a review

Fungicidal Sesquiterpene Dialdehyde Cinnamates from Pseudowintera axillaris

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