Cytotoxicity and genotoxicity evaluation of chemically synthesized and functionalized upconversion nanoparticles

Carrier-Free Self-Assembled Nanomedicines for Promoting Apoptosis and Inhibiting Proliferation in Hepatocellular Carcinoma

“…In addition, Figure d shows the heating and cooling cycles of the BI NPs, from which it can be seen that the warming amplitude is almost unchanged after five cycles, indicating that the BI NPs have good thermal stability. In addition, the photothermal conversion efficiency (PCE) calculated at 808 nm laser wavelength according to an equation , was 32.8% (Figure S1). In summary, the BI NPs have good photothermal conversion and photostability in PTT.…”

“…However, most of the nanocarriers used for loading drugs exhibit very low loading capacity because the nanocarriers themselves account for a much larger proportion of the nanoparticles than the drug. , In addition, the preparation of nanocarriers is a complex, hazardous, and energy-consuming process, including the use of organic solvents, high temperatures and pressures required for synthesis, and so on, which may lead to quality problems due to the variations in the process from batch to batch. , Self-assembled nanoparticles have the advantages of nanoscale drug delivery systems and a high drug loading capacity. Generally, small-molecule drugs spontaneously combine into supramolecular structures through noncovalent interactions, which have the advantages of good physicochemical properties, desirable activity, and a rapid and simple preparation process. − …”

Potential Biomedical Applications of Terbium-Based Nanoparticles (TbNPs): A Review on Recent Advancement

“…In addition, very few significant studies indicate the potential toxicity of TbNPs in biological systems. In the dynamic realm of biomedical research, TbNPs have emerged as promising contenders for a plethora of applications, ranging from targeted drug delivery to advanced imaging modalities. , However, as we navigate the exciting potential of TbNPs in the biomedical landscape, it becomes imperative to scrutinize and understand the subtle toxicological concerns that may accompany their integration into biological systems. , Drawing from the convergence of nanotechnology and medicine, we delve into the multifaceted interactions between TbNPs and biological entities, focusing on ensuring these NPs ’ safety and efficacy in the intricate milieu of the human body. The unique electronic and magnetic properties of TbNPs, which make them attractive for various applications, also raise questions regarding their potential adverse effects on living organisms .…”

Luminescence enhancement through co-sensitization in lanthanide composites for efficient photocatalysis

“…16–18 The material diversity, excitation sources, optical mechanisms, potential applications, and more of these nanocrystals are continuously evolving, providing robust solutions to scientific challenges in both fundamental research and practical applications. 19–30…”