Cytotoxicity and GMI bio-sensor detection of maghemite nanoparticles internalized into cells

Blanc-Béguin, Frédérique; Nabily, S.; Gieraltowski, J.; Turzo, A.; Querellou, Solène; Salaun, Pierre–Yves

doi:10.1016/j.jmmm.2008.08.104

Cited by 68 publications

(50 citation statements)

References 30 publications

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“…Sensitivities of GMI sensors can be very high; for example, the GMI response of CoFeSiB-alloy nanowires around 15 lm in diameter can reach 40-100% per Oe [100]. However, the range of sensitivity can be limited; the GMI response falls off quickly with magnetic field, but improved alloys and fabrication techniques have resulted in nanowires which show over 100% GMI over a range of ±50-80 Oe [20].…”

Section: Magnetoimpedance Biosensorsmentioning

confidence: 99%

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Magnetic biosensor technologies for medical applications: a review

Llandro

Palfreyman

Ionescu

et al. 2010

Med Biol Eng Comput

204

117

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In this review we discuss conventional methods of performing biological assays and molecular identification and highlight their advantages and limitations. An alternative approach based on magnetic nanotechnology is then presented. Firstly, magnetic carriers are introduced and their biocompatibility and functionalisation discussed, with spotlights on functionalisation via self assembled monolayers and on methods of reducing nonspecific binding. In addition an introduction is provided to the basic physical concepts behind the various types of sensors used to detect magnetic labels. Finally, progress in the field of magnetic biosensors and the outlook for the future are discussed.

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Section: Magnetoimpedance Biosensorsmentioning

confidence: 99%

“…GMI biosensors have been used to detect thin ferrofluid layers [87], magnetic microbeads [26,86] and also Fe 3 O 4 nanoparticles taken up (in large numbers) by human cells [20,84]. However, as GMI is dependent on the effective skin depth, it is also sensitive to surface modification of the nanowires.…”

Section: Magnetoimpedance Biosensorsmentioning

confidence: 99%

Magnetic biosensor technologies for medical applications: a review

Llandro

Palfreyman

Ionescu

et al. 2010

Med Biol Eng Comput

204

117

View full text Add to dashboard Cite

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“…[1][2][3][4] As a relatively new kind of magnetic sensor, the thin film giant magnetoimpedance (GMI) sensor has been extensively studied in the past decade because of its high magnetic field sensitivity, capability of integration in microfabricated devices, as well as the fact that it is driven by an AC current. [5][6][7][8][9][10][11][12][13][14] The AC operation provides the possibility to combine GMI thin film sensors with transducers, which respond to RF signals, for example, surface acoustic wave (SAW) devices. SAW devices have been widely used either as sensors or in combination with sensors as a transponder to enable passive and remote operation.…”

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confidence: 99%

Integration of thin film giant magnetoimpedance sensor and surface acoustic wave transponder

Salem

Giouroudi

et al. 2012

Journal of Applied Physics

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Passive and remote sensing technology has many potential applications in implantable devices, automation, or structural monitoring. In this paper, a tri-layer thin film giant magnetoimpedance (GMI) sensor with the maximum sensitivity of 16%/Oe and GMI ratio of 44% was combined with a two-port surface acoustic wave (SAW) transponder on a common substrate using standard microfabrication technology resulting in a fully integrated sensor for passive and remote operation. The implementation of the two devices has been optimized by on-chip matching circuits. The measurement results clearly show a magnetic field response at the input port of the SAW transponder that reflects the impedance change of the GMI sensor.

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“…For similar sensitivity, at higher scanning speeds, fluxgate sensors higher thermal stability, improved linearity and tractability in comparison to giant magneto impedance sensors [21]. Giant magneto impedance sensors have been successfully applied towards detection of biomarkers such as MAT-Ly-Lu [22], human papilloma virus type 16/18 [23] and gastric cancer cells [24]. In an effort to improve detection due to the advantages associated with the fluxgate sensor, in this paper, a MEMS based fluxgate sensor for the detection of pathogenic bacteria conjugated to magnetic beads is presented.…”

Section: Introductionmentioning

confidence: 99%