Cytotoxicity of 45S5 bioglass paste used for dentine hypersensitivity treatment

Surface pre-conditioning with bioactive glass air-abrasion can enhance enamel white spot lesion remineralization

“…In vitro and in vivo studies demonstrated that BAG 45S5 allowed close contact of the living cells at its surface and did not contain leachables which produce inflammation [11]. It has been shown that BAG 45S5 mixture prepared to treat dentin hypersensitivity and incipient enamel caries is a biocompatible material concluded by assessing the viability and the morphological alternations of pulp cells [12]. The remineralization of enamel WSL is a complex physicochemical process where the remaining mineral crystals are less reactive, covered by salivary proteins and the limited diffusion of ions lessens the net mineral gain [13][14][15].…”

Remineralizing effect of cold plasma and/or bioglass on demineralized enamel

“…It is worth mentioning that bioglass is a highly biocompatible material when tested on pulp cells 31) and it can safely be used for longer periods, should full mineral recovery be attempted. Contrariwise, NaF varnish is not recommended for prolonged use on teeth, as it might diffuse to the gingival or periodontal tissues and cause adverse effects.…”

Mechanical characteristic and biological behaviour of implanted and restorative bioglasses used in medicine and dentistry: A systematic review

“…Nevertheless, 45S5 bioglasses are applied also to non-permanent materials especially used in dentistry. BG-pastes are favourable for the treatment of dentin hypersensitivity [6], enamel demineralization [7] and for tooth bleaching [8]. Finally, bioactive glasses have satisfying characteristics as a scaffold material for bone tissue engineering, but the application of glass scaffolds for the load-bearing bone defects reparation is often limited by their low mechanical strength and fracture toughness.…”