Cytotoxicity of aluminium oxide nanoparticles towards fresh water algal isolate at low exposure concentrations

Pakrashi, Sunandan; Dalai, Swayamprava; Prathna, T.C.; Trivedi, Shruti; Myneni, Radhika; Raichur, Ashok M.; Chandrasekaran, N.; Mukherjee, Amitava

doi:10.1016/j.aquatox.2013.01.018

Cited by 117 publications

(54 citation statements)

References 51 publications

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“…Nanoparticles of gold are capable of interfering in electron dissipation processes in PSII (Caires et al, 2010), similarly, aluminum nanoparticles are able to induce toxic effects related to interaction between the particles and the surface active sites on the cell wall (Sadiq et al, 2011) but these ANPs are infinitely larger compared with ions. Some stress responses are related to Al 3+ ions released from ANPs in the medium playing a predominant role on cytotoxicity (Pakrashi et al, 2013).…”

Section: Resultsmentioning

confidence: 99%

Chlorophyll a fluorescence in two varieties of sugar cane subjected to aluminum and water stress

Ecco¹,

Santiago²,

Lima³

2013

Afr. J. Agric. Res

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Soils of open pasture in the Cerrado (brazilian savanna) have farming limitations related to the high content of aluminum and water restrictions in the superficial horizons, due to easy drainage and large exposure to high levels of irradiance. Aiming to assess chlorophyll a fluorescence's responses in two varieties of sugar cane in the State of Mato Grosso do Sul subjected to water restriction and different aluminum contents, an experiment was conducted in a controlled environment. The experimental lineation consisted of random blocks in a factorial scheme (2 varieties x 2 levels of water available in the soil based on field capacity [cc] and 3 contents of Al +3 ), with 15 replications. Significant differences were observed throughout and at the end of the experiment between the averages of some parameters of chlorophyll a fluorescence for treatment EH1 and between varieties. Results obtained by means of the OJIP test were the most efficient for variety distinction. RB1 (RB 8555536) proved to be more responsive to treatments, variety RB2 (RB867515) did not present significant alterations between treatments; its suggests that most part of the radiation was efficiently used in the photochemical stage of photosynthesis, that makes it more tolerant to the subjected stresses.

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Section: Resultsmentioning

confidence: 99%

Chlorophyll a fluorescence in two varieties of sugar cane subjected to aluminum and water stress

Ecco¹,

Santiago²,

Lima³

2013

Afr. J. Agric. Res

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“…Anane and Creppy (2001) and Rao and Stein (2003) have reported that the formation of ROS can result due to the interaction of Al with the cells. The leached out Al 3+ ions and the surface charge-based interaction of Al 2 O 3 NPs may also synergistically modify the surface functional moieties, which thereby result in oxidative stress and cell membrane damage due to the triggering of several signal transduction cascades (Pakrashi et al 2013). Tang et al (2007) have suggested that the increase in the ROS level may thus stimulate the production of the antioxidative enzyme, SOD.…”

Section: Superoxide Dismutase Assaymentioning

confidence: 99%

Cytotoxicity of aluminum oxide nanoparticles on Allium cepa root tip—effects of oxidative stress generation and biouptake

Rajeshwari

Kavitha

Alex

et al. 2015

Environ Sci Pollut Res

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112

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The commercial usage of Al2O3 nanoparticles (Al2O3 NPs) has gone up significantly in the recent times, enhancing the risk of environmental contamination with these agents and their consequent adverse effects on living systems. The current study has been designed to evaluate the cytogenetic potential of Al2O3 NPs in Allium cepa (root tip cells) at a range of exposure concentrations (0.01, 0.1, 1, 10, and 100 μg/mL), their uptake/internalization profile, and the oxidative stress generated. We noted a dose-dependent decrease in the mitotic index (42 to 28 %) and an increase in the number of chromosomal aberrations. Various chromosomal aberrations, e.g. sticky, multipolar and laggard chromosomes, chromosomal breaks, and the formation of binucleate cells, were observed by optical, fluorescence, and confocal laser scanning microscopy. FT-IR analysis demonstrated the surface chemical interaction between the nanoparticles and root tip cells. The biouptake of Al2O3 in particulate form led to reactive oxygen species generation, which in turn probably contributed to the induction of chromosomal aberrations.

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“…Nanoparticle-treated (anatase, rutile and (1, 1) mg/L) and untreated algal cells were stained with 500 L of propidium iodide for about 10 min. Stained algal cells were washed with 2X saline-sodium citrate (SSC) buffer thrice (as detailed in our previous study by Pakrashi et al, 2013). The stained algal cells were observed using confocal laser scanning microscopy (Zeiss LSM 510 META Confocal system, Germany) by employing the emission filter BP, 565-615 nm, and the excitation filter, LP 543 nm.…”

Section: Uptake/internalization Of Ti (Icp-oes)mentioning

confidence: 99%

“…Hence, it becomes necessary to evaluate the toxicity of TiO 2 NPs at its environmentally relevant concentrations. In our previous studies Pakrashi et al, 2013), we have evaluated the toxicity of TiO 2 and Al 2 O 3 NPs under environmentally relevant low-exposure concentrations, i.e., 0.05, 0.5, and 1 mg/L, towards freshwater algae. Microalgae are of great importance for the maintenance of aquatic ecosystem.…”

Section: Introductionmentioning

confidence: 99%

Combined toxicity of two crystalline phases (anatase and rutile) of Titania nanoparticles towards freshwater microalgae: Chlorella sp

et al. 2015

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Cytotoxicity of aluminium oxide nanoparticles towards fresh water algal isolate at low exposure concentrations

Cited by 117 publications

References 51 publications

Chlorophyll a fluorescence in two varieties of sugar cane subjected to aluminum and water stress

Chlorophyll a fluorescence in two varieties of sugar cane subjected to aluminum and water stress

Cytotoxicity of aluminum oxide nanoparticles on Allium cepa root tip—effects of oxidative stress generation and biouptake

Combined toxicity of two crystalline phases (anatase and rutile) of Titania nanoparticles towards freshwater microalgae: Chlorella sp

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