One of the consequences of the Nazi occupation of the Czech Lands in 1939-1945 was that the careers of many scientists and academics either experienced politically and ideologically driven changes or were forcibly ended. Emigration, racial persecution, or involvement in the resistance movement had a fatal impact on the previously multicultural and multilingual scientific community in the Czech Lands. This had a significant effect also on the medical profession. Using the example of some of its elite representatives, namely university teachers (professors and senior lecturers), one can trace the development of an important part of traditional, linguistically German science and education in the Czech Lands. This study contributes to research focused on description and analysis of changes in the scientific and personnel basis of medical science in the Czech Lands during the period in question. It also adds to our knowledge of development of sciences and scientific institutions, in particular at the Faculty of Medicine of the German University in Prague. This contribution is based on the study of materials kept in both domestic and foreign archives.