d-Glucose-1-phosphate: d-glucose-6-phosphotransferase

Fujimoto, Atsuko; Ingram, P. L.; Smith, Rhona

doi:10.1016/0005-2787(65)90613-1

Cited by 17 publications

(5 citation statements)

References 11 publications

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“…Notably, the expression of both the β-glucosidase and glucose-6-phosphate isomerase genes has been found to be significantly higher in the intestinal bacteria of geese compared with those of chickens 30 31 32 33 . The other route from cellobiose to β-D-fructose-6P is first involves transformation into α-D-glucose-1P by cellobiose phosphorylase 34 35 , followed by transformation into α-D-glucose-6P by phosphoglucomutase 36 and, finally, transformation into β-D-fructose-6P by glucose-6-phosphate isomerase 29 . Cellobiose phosphorylase was only found in the gut microbiota, while phosphoglucomutase was identified in the goose genome, and glucose-6-phosphate isomerase was also present in the goose genome and was expressed in the intestinal bacteria of geese significantly more highly than in those of chickens.…”

Section: Resultsmentioning

confidence: 99%

Genome and metagenome analyses reveal adaptive evolution of the host and interaction with the gut microbiota in the goose

Gao

Zhao

Qin

et al. 2016

Sci Rep

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The goose is an economically important waterfowl that exhibits unique characteristics and abilities, such as liver fat deposition and fibre digestion. Here, we report de novo whole-genome assemblies for the goose and swan goose and describe the evolutionary relationships among 7 bird species, including domestic and wild geese, which diverged approximately 3.4~6.3 million years ago (Mya). In contrast to chickens as a proximal species, the expanded and rapidly evolving genes found in the goose genome are mainly involved in metabolism, including energy, amino acid and carbohydrate metabolism. Further integrated analysis of the host genome and gut metagenome indicated that the most widely shared functional enrichment of genes occurs for functions such as glycolysis/gluconeogenesis, starch and sucrose metabolism, propanoate metabolism and the citrate cycle. We speculate that the unique physiological abilities of geese benefit from the adaptive evolution of the host genome and symbiotic interactions with gut microbes.

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Section: Resultsmentioning

confidence: 99%

Genome and metagenome analyses reveal adaptive evolution of the host and interaction with the gut microbiota in the goose

Gao

Zhao

Qin

et al. 2016

Sci Rep

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“…The A TP:oglucose 6-phosphotransferase (EC 2.7.1.2) catalyses the reaction (Porter & Chassy, 1982 catalysing the reaction (Szymona & Ostrowski, 1964) (phosphate)n + o-glucose ~ (phosphate)n -1 + o-glucose 6-phosphate is only of scientific interest, as is the phosphoglucomutase (o-glucose 1-phosphate: o-glucose 6-phosphotransferase, EC 2.7.5.5; Fujimoto et al, 1965).…”

Section: Introducfionmentioning

confidence: 99%

Glucose Transforming Enzymes

Crueger

1990

Microbial Enzymes and Biotechnology

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“…Phenyl phosphates are effective phosphate donors in several enzyme-atalysed reactions: in the formation of nucleotides (Chargaff & Tunis, 1956), in the phosphorylation of numerous biological alcohols by human acid phosphatase (Meyerhof & Green, 1952) and in the formation of glucose 6-phosphate by a similar acid phosphatase preparation (Vescia, 1959). However, phosphatase-catalysed phosphotransferase reactions generally require high concentrations (1-2M) of non-specific hydroxylic acceptors (Morton, 1953;Nordlie & Arion, 1964;Fujimoto et al, 1965). Our effect is unusual in its pH-dependence and in the low concentrations of glucose necessary to promote it, and on the whole the formation of a glucosyl-enzyme complex, as in model 1, is more compatible with the high specificity of the process than the alternative mechanism of model 2.…”

Section: Possible Mechanisms Of Glucose Stimulation and Inhibitionmentioning

confidence: 99%

Phosphatase synthesis in Klebsiella (Aerobacter) aerogenes growing in continuous culture

Bolton

Dean

1972

Biochemical Journal

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1. Phosphatase synthesis was studied in Klebsiella aerogenes grown in a wide range of continuous-culture systems. 2. Maximum acid phosphatase synthesis was associated with nutrient-limited, particularly carbohydrate-limited, growth at a relatively low rate, glucose-limited cells exhibiting the highest activity. Compared with glucose as the carbon-limiting growth material, other sugars not only altered the activity but also changed the pH-activity profile of the enzyme(s). 3. The affinity of the acid phosphatase in glucose-limited cells towards p-nitrophenyl phosphate (K(m) 0.25-0.43mm) was similar to that of staphylococcal acid phosphatase but was ten times greater than that of the Escherichia coli enzyme. 4. PO(4) (3-)-limitation derepressed alkaline phosphatase synthesis but the amounts of activity were largely independent of the carbon source used for growth. 5. The enzymes were further differentiated by the effect of adding inhibitors (F(-), PO(4) (3-)) and sugars to the reaction mixture during the assays. In particular, it was shown that adding glucose, but not other sugars, stimulated the rate of hydrolysis of p-nitrophenyl phosphate by the acid phosphatase in carbohydrate-limited cells at low pH values (<4.6) but inhibited it at high pH values (>4.6). Alkaline phosphatase activity was unaffected. 6. The function of phosphatases in general is discussed and possible mechanisms for the glucose effect are outlined.

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d-Glucose-1-phosphate: d-glucose-6-phosphotransferase

Cited by 17 publications

References 11 publications

Genome and metagenome analyses reveal adaptive evolution of the host and interaction with the gut microbiota in the goose

Genome and metagenome analyses reveal adaptive evolution of the host and interaction with the gut microbiota in the goose

Glucose Transforming Enzymes

Phosphatase synthesis in Klebsiella (Aerobacter) aerogenes growing in continuous culture

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