DAC Target Policy Profile (TPoP)

Dolley, Shawn; Hartman, Dan; Norman, Thea; Hudson, Ian

doi:10.48060/tghn.2

Cited by 4 publications

(4 citation statements)

References 26 publications

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“…We sorted the evidence descriptions identified from the review into broad groupings informed by the WHO 2017 guidelines for preventative chemotherapy for STH and a prior TPoP developed for other initiatives (17,19). These groupings were henceforth referred to as "evidence categories".…”

Section: Methodsmentioning

confidence: 99%

“…A similar initiative was undertaken to identify vaccine-related evidence anticipated to facilitate global policy recommendations (28). The Evidence Considerations for Vaccine Policy (ECVP) initiative, based on a tool developed by the Bill & Melinda Gates Foundation called the Target Policy Profile, developed a tool to identify the anticipated clinical trial and observational data or evidence that could support WHO and/or policy decision making for new vaccines (17). Like the ECVP, the STH TPoP does not preclude or supersede independent guideline convenings or GRADE-based recommendations.…”

Section: Sth Stakeholders Generally Endorse More Detailed Information...mentioning

confidence: 99%

“…As increasing evidence is emerging suggesting the possibility of interrupting the transmission of STH and the recognition that a shift in future STH guidelines towards transmission interruption would require updates to future guidelines, we aimed to engage with STH stakeholders to develop a target policy profile (TPoP). The purpose of the TPoP is to systematically describe the optimal characteristics and requirements of evidence to include in clinical and operational guidelines for future potential STH transmission interruption efforts (17). A TPoP would in no way replace established WHO or national-level guideline development processes.…”

Section: Introductionmentioning

confidence: 99%

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Participatory development of a target policy profile to support soil-transmitted helminth elimination

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et al. 2024

Front. Health Serv.

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IntroductionSoil-transmitted helminths (STH) are parasitic worms that infect nearly a quarter of the world's population, particularly those living in communities without access to adequate water, sanitation, and housing. Emerging evidence suggests that it may be possible to interrupt transmission of STH by deworming individuals of all ages via community-wide MDA (cMDA), as opposed to only treating children and other focal populations. Transitioning from a policy of STH control to STH elimination in targeted areas would require a fundamental shift in STH policy and programming. This policy change would require updated guidance to support countries as they adapt their current approaches for STH surveillance, supply chain management, community mobilization, and core programmatic activities in pursuit of STH elimination. There is an opportunity to engage with key stakeholders, such as program implementers and implementation partners, to understand what evidence they need to confidently adopt a new policy guideline and to deliver guideline adherent management at scale.MethodsWe aimed to engage with STH stakeholders to develop a Target Policy Profile (TPoP), a single document that describes optimal characteristics and evidence requirements that STH stakeholders prioritized in future potential STH transmission interruption efforts. Steps in TPoP development included a scoping review and key informant interviews (KIIs), which were used to design a two-stage Delphi technique to identify and verify TPoP components.ResultsThe scoping review resulted in 25 articles, and 8 experts participated in KII's. Twenty respondents completed the first Delphi survey and 10 respondents completed the second. This systematic effort resulted in a net of 3 key information domains (background/context, clinical considerations, and implementation considerations) encompassing 24 evidence categories (examples include evidence regarding safety and adverse events, implementation feasibility, or evidence dissemination). For each evidence category, STH stakeholders reviewed, endorsed, or revised a range of options for how the evidence could be presented.DiscussionThis information can be used by guideline committees or global policy makers prior to convening guideline advisory groups. The TPoP tool may also speed the process of stakeholder consensus building around guidelines, accelerating progress towards implementing evidence-based policy at scale.

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Section: Methodsmentioning

confidence: 99%

Section: Sth Stakeholders Generally Endorse More Detailed Information...mentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Participatory development of a target policy profile to support soil-transmitted helminth elimination

Means,

List,

Roll

et al. 2024

Front. Health Serv.

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“…While the term was first mentioned in 2017, no package of attributes or sections was published at the time. In 2020, the TPoP was released publicly (Dolley, et al 2020). In 2021, the WHO was introduced to the tool, and used it as a basis for their Evidence Considerations for Vaccine Policy (Kochhar, et al 2022).…”

Section: Background: the Target Policy Profilementioning

confidence: 99%

Target Policy Profile (TPoP)

Dolley¹,

Hartman²,

Norman³

2023

Preprint

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The Target Policy Profile (TPoP) is a tool to aid discussion on the evidence needed to change or establish a new policy. This policy could be at the country, regional, or global level. The TPoP should state the proposed policy, the supporting evidence, gaps in the evidence, and the nature of evidence required to fill these gaps. The TPoP should serve as a framework for dialogue and alignment between key stakeholders in the policy development process. By laying out a roadmap to intended policy impact, this tool can also support funding decisions for a particular research agenda.

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