In early 2020, the novel coronavirus, COVID-19, hit the global community, throwing social disparities into stark relief. With dramatic medical, social, cultural, economic, and environmental effects, the disease has revealed the liability inherent in structuring our social worlds around unequal access to resources, and unequal burdens of work and home. The ability to follow public health guidelines is unevenly distributed both between and within societies. And on the global level, nations have different access to testing and treatment. As we write this, some in primarily wealthier nations are receiving vaccinations, while others are far from this stage. All of this reveals how inequalities have been exacerbated by the disaster, while also making it more difficult for the global community to mitigate COVID-19.In this symposium, we focus on how gender inequalities in particular have structured social life during this global pandemic. At all levels, gender is a central part of the story of COVID-19-from how people experience the disease to how national decisions have been shaped by cultures of manhood. And from the rate of disease, and how men respond to public health calls, to what homelife looks like for people during shutdown, and nationalistic political responses, masculinity has been a unique liability to the human population during this time.At the beginning of the pandemic, men and women appeared to be contracting COVID-19 at similar rates. Men, however, were much more likely to die. Medical opinions piled up. As it turns out, the answer to why has more to do with risky behaviors-like smoking and drinking-in which men are more likely to participate, rather than with male biology (Hamer et al. 2020;Peckham et al. 2020). Compounding this, men's reported beliefs surrounding COVID-19 globally are surprising considering the scope and scale of the pandemic. A survey of 67 nations found that women more often than men said that they fear "very serious" outcomes if infected (Babalola et al. 2020). Yet men ought to be more fearful, as the disease is more fatal