The Neoproterozoic successions of the São Francisco Craton are primarily represented by the Bambuí and Una groups, deposited in cratonic epicontinental basins, and by the Vazante and Vaza Barris/Miaba groups, which accumulated on passive margins on the edges of the craton. The epicontinental basins comprise three megasequences: glaciogenic, carbonate platform (marine) and dominantly continental siliciclastics. Possible correlative sequences are observed in the passive margin deposits. At least two major transgressive-regressive sea-level cycles occurred during the evolution of the carbonate megasequence, which lies above glaciomarine diamictites of probable early Cryogenian (i.e. Sturtian) age. C, O, Sr and S isotope trends from analyses of well-preserved samples, together with lithostratigraphic observations, provide reasonable correlations for most of the Neoproterozoic successions of the São Francisco Craton. The 87 Sr/ 86 Sr record of these successions, ranging from 0.70769 to 0.70780, supports the proposed correlation with the Bambuí, Una and Vaza/Barris successions, and with the basal units of the Vazante Group. In addition, C-isotope positive excursions ranging from þ8.7 to þ14‰ and negative excursions from -5.7 to -7‰ VPDB in the Bambuí, Una and Vaza-Barris successions provide key markers for correlations. The precise ages of the sedimentation in these successions remains a matter of debate, but organic shales of two units of the Vazante Group have been dated by Re-Os techniques in two different laboratories, both yielding Mesoproterozoic ages. The Neoproterozoic and Mesoproterozoic successions preserve significant glaciogenic deposits.