Climate change is one of the trending terms in the world nowadays due to its profound impact on human health and activity. Extreme drought events and desertification are some of the results of climate change. This study utilized the power of AI tools by using the long short-term memory (LSTM) model to predict the drought index for Anbar Province, Iraq. The data from the standardized precipitation evapotranspiration index (SPEI) for 118 years have been used for the current study. The proposed model employed seven different optimizers to enhance the prediction performance. Based on different performance indicators, the results show that the RMSprop and Adamax optimizers achieved the highest accuracy (90.93% and 90.61%, respectively). Additionally, the models forecasted the next 40 years of the SPEI for the study area, where all the models showed an upward trend in the SPEI. In contrast, the best models expected no increase in the severity of drought. This research highlights the vital role of machine learning models and remote sensing in drought forecasting and the significance of these applications by providing accurate climate data for better water resources management, especially in arid regions like that of Anbar province.