2023
DOI: 10.1038/s41522-023-00453-w
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Daily fluctuation of colonic microbiome in response to nutrient substrates in a pig model

Hongyu Wang,
Rongying Xu,
Qiuke Li
et al.

Abstract: Studies on rodents indicate the daily oscillations of the gut microbiota have biological implications for host. However, the responses of fluctuating gut microbes to the dynamic nutrient substrates are not fully clear. In the study, we found that the feed intake, nutrient substrates, microbiota and metabolites in the colon underwent asynchronous oscillation within a day. Short-chain fatty acids (SCFAs) including acetate, propionate, butyrate and valerate peaked during T24 ~ T27 (Timepoint 24, 12:00 pm, T27, 03… Show more

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Cited by 9 publications
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