Daily home haemodialysis in the Netherlands; effects on metabolic control, heamodynamics, and quality of life

Kooistra, Menno P.; Vos, J. Y. De; Koomans, Hein A.; Vos, Pieter C.

doi:10.1093/ndt/13.11.2853

Cited by 205 publications

(175 citation statements)

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“…Similarly, the investigators from the Adequacy of Peritoneal Dialysis in Mexico study found no long-term beneficial effect in QOL by increasing peritoneal small solute clearance in their study population (23). In contrast, enthusiastic reports of improved QOL with intensive hemodialysis have been observed using before-and-after designs (24,25). In the context of the results of this study, how does one reconcile the lack of increased benefits in QOL for patients who undergo NHD compared with PD?…”

Section: Discussionmentioning

confidence: 71%

Cross-Sectional Comparison of Quality of Life and Illness Intrusiveness in Patients Who Are Treated with Nocturnal Home Hemodialysis versus Peritoneal Dialysis

Fong

Bargman

Chan

2007

Clinical Journal of the American Society of Nephrology

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Section: Discussionmentioning

confidence: 71%

Cross-Sectional Comparison of Quality of Life and Illness Intrusiveness in Patients Who Are Treated with Nocturnal Home Hemodialysis versus Peritoneal Dialysis

Fong

Bargman

Chan

2007

Clinical Journal of the American Society of Nephrology

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“…[46][47][48][49][50][51][52][53][54][55][56][57] The studies with strong designs included four comparative observational studies 16,42,44,45 and two systematic reviews.…”

Section: Resultsmentioning

confidence: 99%

Systematic review of the effectiveness and cost-effectiveness, and economic evaluation, of home versus hospital or satellite unit haemodialysis for people with end-stage renal failure

Mowatt

Vale

Perez

et al. 2003

Health Technol Assess

168

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“…4 This view has been supported primarily by small, uncontrolled studies describing very low vascular access event rates with daily and nocturnal hemodialysis. [5][6][7][8] Two nonrandomized studies suggested that, compared with conventional dialysis, daily dialysis is associated with a five-fold decrease in access complications. 9,10 However, two literature reviews suggested the opposite.…”

Section: Discussionmentioning

confidence: 99%

Risk of Vascular Access Complications with Frequent Hemodialysis

Suri

Larive

Sherer

et al. 2013

Journal of the American Society of Nephrology

151

110

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Frequent hemodialysis requires using the vascular access more often than with conventional hemodialysis, but whether this increases the risk for access-related complications is unknown. In two separate trials, we randomly assigned 245 patients to receive in-center daily hemodialysis (6 days per week) or conventional hemodialysis (3 days per week) and 87 patients to receive home nocturnal hemodialysis (6 nights per week) or conventional hemodialysis, for 12 months. The primary vascular access outcome was time to first access event (repair, loss, or access-related hospitalization). Secondary outcomes were time to all repairs and time to all losses. In the Daily Trial, 77 (31%) of 245 patients had a primary outcome event: 33 repairs and 15 losses in the daily group and 17 repairs, 11 losses, and 1 hospitalization in the conventional group. Overall, the risk for a first access event was 76% higher with daily hemodialysis than with conventional hemodialysis (hazard ratio [HR], 1.76; 95% confidence interval [CI], 1.11-2.79; P=0.017); among the 198 patients with an arteriovenous (AV) access at randomization, the risk was 90% higher with daily hemodialysis (HR, 1.90; 95% CI, 1.11-3.25; P=0.02). Daily hemodialysis patients had significantly more total AV access repairs than conventional hemodialysis patients (P=0.011), with 55% of all repairs involving thrombectomy or surgical revision. Losses of AV access did not differ between groups (P=0.58). We observed similar trends in the Nocturnal Trial, although the results were not statistically significant. In conclusion, frequent hemodialysis increases the risk of vascular access complications. The nature of the AV access repairs suggests that this risk likely results from increased hemodialysis frequency rather than heightened surveillance.

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Daily home haemodialysis in the Netherlands; effects on metabolic control, heamodynamics, and quality of life

Abstract: DHHD compared to conventional thrice-weekly haemodialysis with similar weekly Kt/V results in an improved haemodynamic control and quality of life, but has lesser impact on metabolic regulation.

Cited by 205 publications

References 0 publications

Cross-Sectional Comparison of Quality of Life and Illness Intrusiveness in Patients Who Are Treated with Nocturnal Home Hemodialysis versus Peritoneal Dialysis

Cross-Sectional Comparison of Quality of Life and Illness Intrusiveness in Patients Who Are Treated with Nocturnal Home Hemodialysis versus Peritoneal Dialysis

Systematic review of the effectiveness and cost-effectiveness, and economic evaluation, of home versus hospital or satellite unit haemodialysis for people with end-stage renal failure

Risk of Vascular Access Complications with Frequent Hemodialysis

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