Daily Intake of Smallanthus sonchifolius (Yacon) Roots Reduces the Progression of Non-alcoholic Fatty Liver in Rats Fed a High Fructose Diet

Alemán, Mariano Nicolás; Sánchez, Sara S.; Honoré, Stella M.

doi:10.1007/s11130-022-01009-7

Cited by 3 publications

(1 citation statement)

References 32 publications

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“…Alemmán et al [68] investigated the effect of yacon flour on Wistar rats fed a standard diet with the incorporation of a 10% fructose solution. After 20 weeks, the animals were fed yacon flour (340 mg FOS/kg) or fenofibrate (30 mg/kg) for 16 weeks.…”

Section: Antioxidant and Anti-inflammatory Effects Of Yacon Flour: In...mentioning

confidence: 99%

Effects of Smallanthus sonchifolius Flour on Metabolic Parameters: A Systematic Review

Silva,

Bragante,

Junior

et al. 2024

Pharmaceuticals

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Smallanthus sonchifolius, popularly known as yacon, is a member of the Asteraceae family. Due to its medicinal and edible value, yacon is consumed by different populations. Yacon is unique due to its high fructo-oligosaccharide and inulin content, as well as flavonoids, sesquiterpene lactones, and phenolic acids. Roots can be used to produce flour, which is less perishable and can be applied in various industrial products. This systematic review focuses on the effects of yacon flour on metabolic parameters. PubMed, Cochrane, Embase, Science Direct, Scopus, Web of Science, and Google Scholar databases were consulted, and PRISMA guidelines were followed in the selection of the studies. In total, 526 articles were found in the databases, and of these, only 28 full texts were eligible for inclusion. After applying the inclusion and exclusion criteria, seven studies were finally included. The results showed that the use of yacon flour can reduce glycemia, HbA1c, advanced glycation ends, plasma lipids, body fat mass, body weight, and waist circumference and improve intestinal microbiota and the antioxidant status. Further exploration of the effects of yacon flour is warranted, and additional clinical trials are necessary to determine the optimal daily consumption levels required to assist in improving metabolic parameters.

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Section: Antioxidant and Anti-inflammatory Effects Of Yacon Flour: In...mentioning

confidence: 99%

Effects of Smallanthus sonchifolius Flour on Metabolic Parameters: A Systematic Review

Silva,

Bragante,

Junior

et al. 2024

Pharmaceuticals

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Process and quality parameters of convective dried yacon: Influence of ethanol treatment

Silveira,

de P. Silva,

Corrêa

et al. 2024

Food Research International

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Alterations in Oxidative Stress Markers and Na,K-ATPase Enzyme Properties in Kidney after Fructose Intake and Quercetin Intervention in Rats

Vrbjar

Vlkovičová

Snurikova

et al. 2023

Life

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The study aimed to characterize the consequences of a 15-week intake of 10% fructose on the kidney, with the focus on oxidative stress markers and properties of the Na,K-ATPase enzyme. Various antioxidants naturally occurring in common food were demonstrated to be protective against fructose-induced deterioration of kidneys. Therefore, we also aimed to observe the effect of 6-week quercetin administration (20 mg/kg/day) that was initiated following the 9-week period of higher fructose intake, by determining the concentration of sodium, potassium, creatinine, urea, and glucose in blood plasma and oxidative status directly in the renal tissue. Kinetic studies of renal Na,K-ATPase were utilized for a deeper insight into the molecular principles of expected changes in this enzyme activity under conditions of presumed fructose-induced renal injury. Fructose intake led to increase in body weight gain, plasma glucose and sodium levels, and deterioration of kidney properties, although some compensatory mechanisms were observable. Quercetin administration improved glycemic control in rats exposed to fructose overload. However, an increase in plasma creatinine, a decrease in GSH/GSSG ratio in renal tissue homogenate, and a controversial effect on renal Na,K-ATPase enzyme suggest that quercetin treatment may not be beneficial in the condition of pre-existing renal pathology.

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Daily Intake of Smallanthus sonchifolius (Yacon) Roots Reduces the Progression of Non-alcoholic Fatty Liver in Rats Fed a High Fructose Diet

Cited by 3 publications

References 32 publications

Effects of Smallanthus sonchifolius Flour on Metabolic Parameters: A Systematic Review

Effects of Smallanthus sonchifolius Flour on Metabolic Parameters: A Systematic Review

Process and quality parameters of convective dried yacon: Influence of ethanol treatment

Alterations in Oxidative Stress Markers and Na,K-ATPase Enzyme Properties in Kidney after Fructose Intake and Quercetin Intervention in Rats

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