Dairy nutrition: What we knew then to what we know now

MacDonald, Helen Bishop

doi:10.1016/j.idairyj.2008.04.001

Cited by 10 publications

(5 citation statements)

References 39 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…As MacDonald says if asked about a link between milk intake and weight in the past, the likely conclusion was that dairy was ‘fattening’ ( 62 ) . However, with the pioneering work of Zemel ( 63 ) , it has been understood that an energy-restricted diet with the inclusion of at least three servings of dairy per d will help to attain the ideal weight.…”

Section: Relationship Between Dietary Ca2+ and Lipid Metabolismmentioning

confidence: 99%

Molecular mechanisms triggered by low-calcium diets

et al. 2009

View full text Add to dashboard Cite

Ca is not only essential for bone mineralisation, but also for regulation of extracellular and intracellular processes. When the Ca2+ intake is low, the efficiency of intestinal Ca2+ absorption and renal Ca2+ reabsorption is increased. This adaptive mechanism involves calcitriol enhancement via parathyroid hormone stimulation. Bone is also highly affected. Low Ca2+ intake is considered a risk factor for osteoporosis. Patients with renal lithiasis may be at higher risk of recurrence of stone formation when they have low Ca2+ intake. The role of dietary Ca2+ on the regulation of lipid metabolism and lipogenic genes in adipocytes might explain an inverse relationship between dairy intake and BMI. Dietary Ca2+ restriction produces impairment of the adipocyte apoptosis and dysregulation of glucocorticosteroid metabolism in the adipose tissue. An inverse relationship between hypertension and a low-Ca2+ diet has been described. Ca2+ facilitates weight loss and stimulates insulin sensitivity, which contributes to the decrease in the blood pressure. There is also evidence that dietary Ca2+ is associated with colorectal cancer. Dietary Ca2+ could alter the ratio of faecal bile acids, reducing the cytotoxicity of faecal water, or it could activate Ca2+-sensing receptors, triggering intracellular signalling pathways. Also it could bind luminal antigens, transporting them into mucosal mononuclear cells as a mechanism of immunosurveillance and promotion of tolerance. Data relative to nutritional Ca2+ and incidences of other human cancers are controversial. Health professionals should be aware of these nutritional complications and reinforce the dairy intakes to ensure the recommended Ca2+ requirements and prevent diseases.

show abstract

Section: Relationship Between Dietary Ca2+ and Lipid Metabolismmentioning

confidence: 99%

Molecular mechanisms triggered by low-calcium diets

et al. 2009

View full text Add to dashboard Cite

show abstract

“…To avoid the digestive symptoms but keep the dairy in diet the solution can be the lactose-free and low lactose dairy [22]. This leads to a decrease of dairy products consumption, meanwhile they are a key source of calcium in a balanced diet, as well as an important source of protein and set of micronutrients [23,24]. Most guidelines and public health organizations suggest consuming dairy products up to three servings per day to ensure adequate nutrient intakes and optimal bone health [25][26][27][28][29][30].…”

Section: Introductionmentioning

confidence: 99%

Lactase deficiency in Russia: multiethnic genetic study

Kovalenko¹,

Vergasova²,

Shoshina

et al. 2023

Eur J Clin Nutr

View full text Add to dashboard Cite

BackgroundLactase persistence -the ability to digest lactose through adulthood -is closely related to evolutionary adaptations and has affected many populations since the beginning of cattle breeding. Nevertheless, the contrast initial phenotype, lactase non-persistence or adult lactase de ciency, is still affecting large numbers of people worldwide. MethodsWe performed the largest multiethnic genetic study of lactase de ciency on 24439 people in Russia to date. The percent of each population group was estimated according to the local ancestry inference results. Additionally, we calculated frequencies of rs4988235 GG genotype in Russian regions using the information of current location and birthplace data in client's questionnaire. ResultsIt turned out that among all studied population groups the frequency of GG genotype in rs4988235 was higher than in average in the European populations. In particular, the prevalence of lactase de ciency genotype in the East Slavs group was 42.8% (95% CI: 42.1-43.4%). We also investigated the regional prevalence of lactase de ciency by current place of residence. ConclusionsOur study emphasizes the diagnostic signi cance of genetic testing, i.e. speci cally for lactose intolerance parameter, as well as the scale of the problem of lactase de ciency in Russia which needs to be addressed by healthcare and food industry.

show abstract

“…A majority of people consider milk and its products to be dependable sources of calcium, complete proteins, riboflavin, and vitamin A (McDonald, 2008). Dried skimmed milk is made by removing fat and almost all moisture from milk followed by pulverization.…”

Section: Introductionmentioning

confidence: 99%