Dakin—West Synthesis of β‐Aryl Ketones.

Abstract

Ketones Q 0350Dakin-West Synthesis of β-Aryl Ketones. -It is found that N-methylimidazole efficiently promotes the reaction of arylacetic acids (I) and hydrocinnamic acid (V) giving aryl methyl ketones. In the presence of NEt3, the corresponding diaryl ketones are formed predominantly. Branched acid (VIII) and ester (X) do not react. -(TRAN, K.-V.; BICKAR*, D.; J.