In order to avoid the risk of tailing pond failures and to minimize the post-failure losses, it is necessary to analyze the current operation status of tailings ponds, to explore the evolution law of their failure process, to grasp their post-failure impact range, and to propose corresponding effective prevention and control measures. Based on a tailings pond in China, this paper establishes a 1:200 scale indoor model to explore the evolution law of post-failure tailings discharge in a tailings pond under flooded roof conditions; secondly, the finite element difference method and smooth particle fluid dynamics are combined to compare and analyze the post-failure impact area and to delineate the risk prevention and control area. The results of the study show that, during the dam break, the lower tailing sand in the breach is the first to slip, and after forming a steep can, the upper tailing sand in the steep can is pulled to slip, so that the erosion trench mainly develops vertically first, and then laterally. The velocity of the discharged tailing sand will quickly reach its peak value in a short period of time and then decrease to the creeping stage; the front edge of the sand flow is the first to stop moving, and the trailing edge of the tailing sand accumulation depth continues to increase until the end of the dam failure, at which point the initial bottom dam area of the discharge tailing sand flow velocity is the largest. The further the tailings are released from the initial dam, the smaller the accumulation depth and the larger the particle size, and the larger the elevation of the foundation in the same section, the smaller the accumulation depth and the larger the particle size; further, the presence of blocking materials will increase the local tailings accumulation depth. Based on the maximum flow velocity of the discharged tailings and the accumulation depth, the risk area downstream of the tailings pond is divided, so that relocation measures can be formulated. The test results can provide an important reference for the operation and management of similar tailings ponds.