Damage from Carbonated Soft Drinks on Enamel: A Systematic Review

Aims: Medication-related osteonecrosis of the jaw (MRONJ) is a drug-related adverse reaction characterized by bone destruction and necrosis in the jaw. This case series aims to evaluate the treatment approaches and outcomes in MRONJ patients. Materials and methods: The retrospective study was conducted at the Dental Unit of the University of Bari, Italy. Patients with MRONJ were treated and followed up for 60 months. The treatment approach involved piezosurgery and concentrated growth factor (CGF). Six clinical cases from this group are described in detail. Results: None of the patients showed recurrence of necrotic MRONJ lesions during the follow-up period. The surgical interventions, including bone resections and the application of CGF, resulted in successful mucosal healing and the prevention of disease progression. Conclusions: This study highlights the complexity of managing MRONJ and the importance of a multidisciplinary approach. Conservative treatment options and minimally invasive surgery have shown efficacy in controlling symptoms and improving patients’ quality of life. However, the optimal treatment approach remains a challenge, and further studies are needed to evaluate alternative therapies and resective surgery. A comprehensive preoperative evaluation and collaboration among dental, endocrinology, and oncology specialists are crucial for personalized and multidisciplinary management. Ongoing research efforts are necessary to explore new therapeutic modalities and improve our understanding of MRONJ management, providing better support to patients dealing with this complex condition.

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“…In the literature, there are two types of treatment for MRONJ: non-surgical or conservative and surgical [28].…”

Section: Discussionmentioning

confidence: 99%

Sixty-Month Follow Up of Clinical MRONJ Cases Treated with CGF and Piezosurgery

et al. 2023

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“…The role of vitamins, essential micronutrients, has been carefully evaluated in controlling human metabolic functions and also oral health [ 54 ]. Vitamin A, a fat-soluble vitamin, of both plant and animal origin, belongs to the carotenoid group (containing over 600 types), often found in yellow, orange and red vegetables, with powerful antioxidant activity, and controls epithelial integrity and the growth of teeth and bones [ 55 ].…”

Section: Introductionmentioning

confidence: 99%

Benefits of Natural Antioxidants on Oral Health

Malcangi,

Patano,

Ciocia

et al. 2023

Antioxidants

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In recent years, special attention has been paid to the correlation between oxidation–reduction mechanisms and human health. The free radicals produced via physiological cellular biochemical processes are major contributors to oxidation phenomena. Their instability is the major cause of cellular damage. Free radical reactive oxygen species containing oxygen are the best-known ones. The body neutralises the harmful effects of free radicals via the production of endogenous antioxidants (superoxide dismutase, catalase, glutathione, and melatonin). The field of study of nutraucetics has found antioxidant capacity in substances such as vitamins A, B, C, E, coenzyme Q-10, selenium, flavonoids, lipoic acid, carotenoids, and lycopene contained in some foods. There are several areas of investigation that aim to research the interaction between reactive oxygen species, exogenous antioxidants, and the microbiota to promote increased protection via the peroxidation of macromolecules (proteins, and lipids) by maintaining a dynamic balance among the species that make up the microbiota. In this scoping review, we aim to map the scientific literature on oxidative stress related to the oral microbiota, and the use of natural antioxidants to counteract it, to assess the volume, nature, characteristics, and type of studies available to date, and to suggest the possible gaps that will emerge from the analysis.

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“…Accumulating evidence suggests that O.S. associated with orthodontics may have significant clinical implications [ 33 , 34 ]. Additionally, chronic inflammation, caused by orthodontic appliance irritation, can lead to gingivitis and periodontitis, with potentially serious consequences for long-term oral health [ 17 , 35 , 36 , 37 , 38 ].…”

Section: Introductionmentioning

confidence: 99%

Oxidative Stress and Natural Products in Orthodontic Treatment: A Systematic Review

Inchingolo,

Latini

et al. 2023

Nutrients

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In recent years, orthodontics, a specialized branch of dentistry, has evolved considerably in terms of both techniques and materials used. Aimed at correcting dental malocclusions and craniofacial anomalies, it improves the functionality and aesthetics of the face and oral cavity. However, orthodontic treatment, in its developmental stages, may induce oxidative stress (O.S.) phenomena, with an increase in the production of reactive oxygen species (ROS), damaging the dental and periodontal tissues involved, affecting the short-, medium- and long-term results. Studies on the antioxidant effects of natural products (e.g., resveratrol, green tea, turmeric, etc.) in the medical field have aroused considerable interest in recent years. A systematic literature review was conducted on the PubMed, Scopus, and Web of Science databases using natural products (N.P.s), O.S., and orthodontic as keywords. The study aims to consider the determinants of the increase in ROS occurring during orthodontic treatment and the possibility of natural products being able to control and neutralize biochemical phenomena by restoring the physiological process in which the balance between the production of ROS and the ability of the body’s antioxidant system to neutralize them is in favor of the latter.

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Damage from Carbonated Soft Drinks on Enamel: A Systematic Review

Cited by 24 publications

References 92 publications

Sixty-Month Follow Up of Clinical MRONJ Cases Treated with CGF and Piezosurgery

Sixty-Month Follow Up of Clinical MRONJ Cases Treated with CGF and Piezosurgery

Benefits of Natural Antioxidants on Oral Health

Oxidative Stress and Natural Products in Orthodontic Treatment: A Systematic Review

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