The band structure of a type-II Weyl semimetal has pairs of electron and hole pockets that coexist over a range of energies and touch at a topologically protected conical point. We identify signatures of this Weyl point in the magnetic quantum oscillations of the density of states, observable in thermodynamic properties. Tunneling between the electron and hole pockets in a magnetic field is the momentum space counterpart of Klein tunneling at a p-n junction in real space. This magnetic breakdown happens at a characteristic field strength that vanishes when the Fermi level approaches the Weyl point. The topological distinction between connected and disconnected pairs of type-II Weyl cones can be distinguished by the qualitatively different dependence of the quantum oscillations on the direction of the magnetic field. DOI: 10.1103/PhysRevLett.116.236401 Weyl semimetals provide a condensed matter realization of massless relativistic fermions [1]. Their spectrum features a diabolo-shaped surface in energy-momentum space that separates helical electronlike states (moving in the direction of the momentum) from holelike states (moving opposite to the momentum) [2]. These "Weyl cones" are the three-dimensional analogue of the two-dimensional Dirac cones in graphene. The third spatial dimension provides a topological protection, by which the conical point (Weyl point) cannot be opened up unless two Weyl cones of opposite helicity are brought together in momentum space [3].Although the Weyl point cannot be locally removed, the cones can be tilted and may even tip over [4][5][6][7][8][9][10][11][12]. For the relativistic Weyl cone such a distortion is forbidden by particle-hole symmetry, but that is not a fundamental symmetry in condensed matter. While in graphene the high symmetry of the honeycomb lattice keeps the cone upright, strain providing only a weak tilt [13], the tilting can be strong in 3D Weyl semimetals. This leads to a natural division of Weyl cones into two topologically distinct types [9]. In type I the cone is only weakly tilted so that the electronlike states and holelike states occupy separate energy ranges, above or below the Weyl point. In type II the cone has tipped over so that electron and hole states coexist in energy. Many experimental realizations of a type-II Weyl semimetal have recently been reported [14][15][16][17][18][19][20][21].In a magnetic field the coexisting electron and hole pockets of a type-II Weyl semimetal are coupled by tunneling through the Weyl point (Fig. 1). Here we investigate how this process, a momentum space manifestation of Klein tunneling [22], affects the magnetic quantum oscillations of the density of states (de Haas-van Alphen effect), providing a unique thermodynamic signature of the topologically protected band structure (an alternative to proposed transport signatures [9,[23][24][25]). Because the quantum oscillations are governed by extremal cross sections of the Fermi surface, one might wonder whether some symmetry is required to align the extremal cross sect...