Abstract:Propofol is commonly used as a sedative-hypnotic during the induction and maintenance of anesthesia or sedation. Recently, serious side effects have been reported, including an acute anaphylactic reaction to generic propofol that contains sodium bisulfite. This sulfa allergy can cause death if propofol with the bisulfite is used. It behooves the surgeon to make sure that all propofol in use in the outpatient setting does not contain sodium bisulfite. This simple precaution will protect the patient. 83
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