Darier's Disease

Marks, James G.; Thor, Daniel E.; Lowe, Ralph S.

doi:10.1001/archderm.1978.01640210031008

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Etiology and Pathogenesis1

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1982

2002

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Cited by 30 publications

(1 citation statement)

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“…The authors eoneluded that immunologic meehanisms were not of primary significance in the pathogenesis of Darier's disease. Using standard tests, Marks et al (1978) noted decreased cell mediated immunity in their patients with Darier's disease. The role of defects in the immune mechanism in association with Darier's disease needs further investigation.…”

Section: Etiology and Pathogenesismentioning

confidence: 99%

Darier's disease of the oral mucosa: clinical case report with ultrastructural evaluation

Miller

Bernstein

Robert

1982

J Oral Pathology Medicine

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An electron microscopic study of the intraoral lesions of Darier's disease demonstrated a defect of desmosomes and tonofilaments in the early development of affected mucosa. Marked cytoplasmic vacuolation, keratohyaline granule formation and nuclear pyknosis as reported in skin acantholytic cell ultrastructure was not conspicuous in the oral mucosa of the case reported. The clinical diagnosis, histopathologic diagnosis, pedigree and treatment of Darier's disease is discussed.

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Section: Etiology and Pathogenesismentioning

confidence: 99%