Das Auftreten der zentralen pontinen Myelinolyse während des qualifizierten Entzugs von Alkohol. Ein Fallbericht

A primary cilium in oligodendrocytes: a fine structure signal of repairs in thalamic Osmotic Demyelination Syndrome (ODS)

“…This murine investigation model would suggest that a longer time lapse into ODS repairs could be investigated to understand the clinical resolution of such regional CNS neuropathology [1][2][3][4][5][6][7][8][9][10][11][12][13][14][15][16][17][18]219 because similar human ODS clinical cases remained with some concerns even if for most patients the prognosis is generally favorable. 7,[220][221][222] However, a recent retrospective analysis indicated that, post hospitalization, 1 out of 6 ODS patients had died 6 months later, due to other underlying disease states.…”

“…[1][2][3][4][5][6][7][8] The ODS neuropathologic syndrome is caused by a hastily adjustment of a temporary or chronic deficiency of the homeostatic sodium gradient as it can be pertinent to diverse homeostatic hormonal sodic perturbations such as those afflicted by exaggerated body fluid losses and emergently treated for alcoholism, diabetes as well as to defective dialysis. [1][2][3][9][10][11][12][13][14] A large reference list of ODS literature was recently cited [15][16][17][18][19] and it appeared that EPM lesions can appear before any CPM ones [19][20][21][22][23][24][25] and ODS in human EPM cases would be more frequent than CPM ones. 23 There, ODS can frequently appear clinically in the elderly, hospitalized population.…”