Das Auftreten von Zweitkarzinomen im oberen Aerodigestivtrakt bei unterschiedlichen Tumorlokalisationen und Altersgruppen1

Schwager, K.; Nebel, Annika; Baier, G.; Hoppe, Florian

doi:10.1055/s-2000-7675

Cited by 10 publications

(2 citation statements)

References 8 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…상부소화호흡기계 환자에 있어서 이차암(second primary tumors, SPT)의 위험성이 증가한다는 것이 잘 알려져 있다 [1][2][3][4] . 소위 "Field Cancerization" 이론으 로 상부소화호흡기계에서 다발성 종양의 빈도가 높 은 현상을 설명하는 적절한 이론으로 받아들여져 왔 다 5,6 .…”

Section: 서 론unclassified

Clinical Features of Patients with Lung Cancer and Upper Aerodigestive Tract Cancer

et al. 2007

View full text Add to dashboard Cite

Background: To define the clinical features of patients with lung and upper aerodigestive tract cancer through a review of the histopathology, clinical features and follow-up results. Methods: Patients with lung and upper aerodigestive tract cancer who were diagnosed in Young dong Severance Hospital from 1992 to 2005, were retrospectively reviewed. The clinical data, radiologic findings, pathologic findings, treatment modalities were evaluated. Result: There was a total of 20 patients with aerodigestive tract cancer who were diagnosed with lung cancer over a 13 years period. The mean age was 58.45 ±15.09 years and 19 cases were male. There were 14 smokers with an average pack year of 46 years. Twelve patients had aerodigestive tract cancer and later developed lung cancer, and 5 lung cancer patients were later diagnosed with aerodigestive tract cancer. Conclusion: These results suggest that cancers of the aerodigestive tract and lung can arise as either dependent or independent events and most aerodigestive tract cancer patients who developed lung cancer are not treated properly. Therefore, regular low dose chest CT with close suspicion is needed to properly manage upper aerodigestive tract cancer patients.

show abstract

Section: 서 론unclassified

Clinical Features of Patients with Lung Cancer and Upper Aerodigestive Tract Cancer

et al. 2007

View full text Add to dashboard Cite

show abstract

“…In der Lite ratur wird das Auftreten syn bzw. meta chroner Zweitkarzinome im oberen Ae rodigestivtrakt mit bis zu 17% beziffert[14].Deshalb ist auch der Ausschluss von Zweitkarzinomen durch eine HNOärzt liche Endoskopie des oberen Aerodiges tivtrakts (Panendoskopie) Teil des prä operativen Stagings. Die bildgebende Diagnostik zur Darstel lung des Lokalbefundes beinhaltet in der Regel ein KopfHalsCT.…”

unclassified

Mundschleimhautkarzinom

Metz

Pförtner

Schmeling

et al. 2012

best practice onkologie

View full text Add to dashboard Cite

Risk factors for the development of second primary tumors among men after laryngeal and hypopharyngeal carcinoma

Dikshit

Boffetta

Bouchardy³

et al. 2005

Cancer

View full text Add to dashboard Cite

BACKGROUND Second primary tumors (SPT) constitute a major threat to the survival of patients with laryngeal carcinoma. However, to the authors' knowledge little is known regarding the risk factors for developing SPTs or about the strategy to be followed to avoid them. METHODS Eight hundred seventy‐six male patients with laryngeal/hypopharyngeal carcinoma enrolled in a population‐based, case–control study in 5 centers from South Europe during 1979–1982 were followed up to ascertain the occurrence of SPTs. Standardized incidence ratios were calculated to estimate the risk of SPT occurring in the cohort. Cox proportional hazard models were fitted to estimate the hazard ratio for development of SPTs in relation to use of tobacco smoking, alcohol consumption, and dietary habits before the first primary tumor. RESULTS One hundred forty‐five patients developed an SPT with an annual average rate of 2.1%. An excess risk of developing an SPT of the tongue, mouth, esophagus, and lung was observed. No elevated risks of SPTs were observed in other organs. Alcohol consumption strongly increased the risk of developing an SPT of the upper aerodigestive tract (UADT). Heavy cumulative cigarette smoking increased the risk of developing a lung SPT. A protective effect of high intake of citrus fruit was noticed for SPT in the lung, whereas high butter intake was associated with an increased risk for SPT of the UADT. CONCLUSIONS Continuous medical surveillance was essential in the UADT and lung to reduce the risk from an SPT after initial laryngeal/hypopahryngeal carcinoma. Alcohol consumption before the first primary tumor was a risk factor for SPT of the UADT. The study suggested a protective role of citrus fruits in the development of a lung SPT. Cancer 2005. © 2005 American Cancer Society.

show abstract

Das Auftreten von Zweitkarzinomen im oberen Aerodigestivtrakt bei unterschiedlichen Tumorlokalisationen und Altersgruppen1

Abstract: The results demonstrate that younger patients and patients with carcinomas of the upper digestive tract need a consequent follow-up. The development of second primaries even years after the first malignoma demonstrates the necessity of lifelong follow-up and oncological care.

Cited by 10 publications

References 8 publications

Clinical Features of Patients with Lung Cancer and Upper Aerodigestive Tract Cancer

Clinical Features of Patients with Lung Cancer and Upper Aerodigestive Tract Cancer

Mundschleimhautkarzinom

Risk factors for the development of second primary tumors among men after laryngeal and hypopharyngeal carcinoma

Contact Info

Product

Resources

About