Das Beratungsgeheimnis

Coelln, Carl Günther von

doi:10.1007/978-3-642-94194-8

Cited by 1 publication

(2 citation statements)

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“…Another popular option is to combine the levodopa prescription with surgeries such as deep brain stimulation (DBS), focused ultrasound thalamotomy (FUS-T), and light-activated optogenetic surgeries. DBS is a surgical treatment for PD that targets the subthalamic nucleus (STN) and reduces the effects of LID because the dosage of levodopa can be lowered after the surgery (Von Coelln, 2021). The DBS provides electrical stimulation in the brain to create an action potential for dopaminergic neurons, which means that the dopamine neurons are able to fire without receiving stimulation from actual dopamine.…”

Section: Side Effects Of Levodopamentioning

confidence: 99%

“…FUS-T is a good option for those who cannot or do not want to have the DBS surgery because it is less expensive, less invasive, and uses less batteries. Unfortunately, FUS-T is currently only approved for procedure on one side of the brain and may not have satisfactory results as this means only one side of the body's motor movements will improve (Von Coelln, 2022). A clinical trial for approval to be used on both sides is currently underway.…”

Section: Side Effects Of Levodopamentioning

confidence: 99%

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Alternative Treatment Options to Levodopa and Carbidopa for Parkinson’s Disease Patients

Kwon¹,

Wang

Sharbaugh³

2022

J Stud Res

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The most commonly used treatment for Parkinson’s Disease (PD) is levodopa used in conjunction with carbidopa. Despite being able to alleviate the motor symptoms of PD, it is unable to slow down the progression of the disease or give neuroprotective effects. There is no effective cure for PD or any treatment that is able to prevent the advancement of Parkinson’s pathology. The purpose of this research was to examine different combinations of treatments and medications that provide best results for patients and investigate novel research that is conducted in order to target the causes of PD, rather than its effects and symptoms. Interviews of doctors were conducted in order to determine the most commonly used treatments and what they have had success with when treating patients. The results revealed that levodopa still remains the most effective treatment, but its effects can be improved by adjunctive medications or therapies. Recent research also suggests that drugs that target other factors of PD pathology separate from dopaminergic neurons provide more neuroprotective effects and may be able to prevent the progression of the disease.

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Section: Side Effects Of Levodopamentioning

confidence: 99%

Section: Side Effects Of Levodopamentioning

confidence: 99%