Das Long-COVID-Syndrom – ein neues Krankheitsbild nach                COVID-19-Infekt

Funke-Chambour, Manuela; Feldmeyer, Laurence; Hoepner, Robert; Huynh‐Do, Uyen; Maurer, Britta; Rexhaj, Emrush; Geiser, Thomas

doi:10.1024/1661-8157/a003678

Cited by 6 publications

(3 citation statements)

References 48 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Approximately, 25%–35% of patients have not returned to baseline renal function at the time of hospital discharge and had a new onset or a more severe chronic kidney disease (CKD) than they did before their COVID‐19 infection 5,6 . Some researchers proposed the process of kidney involvement from acute to chronic after SARS‐CoV‐2 infection 13–15 . However, the exact mechanism remains unclear.…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

The pattern of cytokines expression and dynamic changes of renal function at 6 months in patients with Omicron COVID‐19

Teng

Song

Zhang

et al. 2023

Journal of Medical Virology

View full text Add to dashboard Cite

To analyze the dynamic changes of renal function longitudinally and investigate the cytokine profiles at 6 months in patients with Omicron COVID‐19. Forty‐seven patients with a proven diagnosis of Omicron COVID‐19 from January to February 2022 attended a 6‐month follow‐up after discharge at Tianjin First Central Hospital. The demographic parameters, clinical features, and laboratory indexes were collected during hospitalization and 6 months after discharge. The serum cytokine levels at 6 months were also assessed. Patients were grouped according to with or without kidney involvement at admission. The levels of serum creatinine and estimated glomerular filtration rate (eGFR) were all normal both in the hospital and at follow‐up. Whereas, compared with renal function in the hospital, serum creatinine levels at 6 months increased remarkably; meanwhile, eGFR decreased significantly in all patients. The serum levels of interleukin (IL)‐2, IL‐4, IL‐5, IL‐6, IL‐10, and TNF‐α and IFN‐γ significantly decreased and TGF‐β remarkably increased in the kidney involvement group. The serum levels of IL‐2 and IL‐5 were positively correlated with age; contrarily, TGF‐β showed a negative correlation with aging. The younger was an independent risk factor of the higher TGF‐β levels. Omicron patients showed a decline in renal function at follow‐up, reflecting the trend of CKD. Serum cytokine profiles were characterized with the majority of cytokines decreased and TGF‐β increased in the kidney involvement group; the latter may be used as a sign of CKD. The tendency of CKD is one of the manifestations of long COVID and deserves attention.

show abstract

Section: Introductionmentioning

confidence: 99%

“…5,6 Some researchers proposed the process of kidney involvement from acute to chronic after SARS-CoV-2 infection. [13][14][15] However, the exact mechanism remains unclear. Studies have assumed that persistent and abnormal immune inflammatory responses triggered by the SARS-CoV-2 infection might play an important role.…”

mentioning

confidence: 99%

The pattern of cytokines expression and dynamic changes of renal function at 6 months in patients with Omicron COVID‐19

Teng

Song

Zhang

et al. 2023

Journal of Medical Virology

View full text Add to dashboard Cite

show abstract

“…Currently, there is no clear and uniform definition of PCC [ 14 ]. According to the National Institute for Health and Care Excellence, 3 different phases of an infection with SARS-CoV-2 should be distinguished [ 10 ].…”

Section: Introductionmentioning

confidence: 99%

The Evaluation of Health Care Services for Children and Adolescents With Post–COVID-19 Condition: Protocol for a Prospective Longitudinal Study

Rathgeb¹,

Pawellek²,

Behrends³

et al. 2023

JMIR Res Protoc

View full text Add to dashboard Cite

Background Some children and adolescents suffer from late effects of a SARS-CoV-2 infection despite a frequently mild course of the disease. Nevertheless, extensive care for post–COVID-19 condition, also known as post–COVID-19 syndrome, in children and young people is not yet available. A comprehensive care network, Post-COVID Kids Bavaria (PoCo), for children and adolescents with post–COVID-19 condition has been set up as a model project in Bavaria, Germany. Objective The aim of this study is to evaluate the health care services provided within this network structure of care for children and adolescents with post–COVID-19 condition in a pre-post study design. Methods We have already recruited 117 children and adolescents aged up to 17 years with post–COVID-19 condition who were diagnosed and treated in 16 participating outpatient clinics. Health care use, treatment satisfaction, patient-reported outcomes related to health-related quality of life (the primary endpoint), fatigue, postexertional malaise, and mental health are being assessed at different time points (at baseline and after 4 weeks, 3 months, and 6 months) using routine data, interviews, and self-report questionnaires. Results The study recruitment process ran from April 2022 until December 2022. Interim analyses will be carried out. A full analysis of the data will be conducted after follow-up assessment is completed, and the results will be published. Conclusions The results will contribute to the evaluation of therapeutic services provided for post–COVID-19 condition in children and adolescents, and avenues for optimizing care may be identified. International Registered Report Identifier (IRRID) DERR1-10.2196/41010

show abstract

Utilization of video consultation in cardiovascular lipid treatment

Schuch,

Walther,

Timm

et al. 2023

Herz

View full text Add to dashboard Cite

Zusammenfassung Hintergrund Die Videosprechstunde ist eine Möglichkeit der ortsunabhängigen Arzt-Patienten-Kommunikation. Bei Möglichkeit der alleinigen Anwendung seit 2018 liegen jedoch nur eingeschränkte Informationen vor. Methoden Nach Einführung der Videosprechstunde (Viomedi) in der Lipidsprechstunde der Universitätsmedizin Mainz wurden die Patienten im Q1-2022 nach Möglichkeit, Eignung und Bereitschaft zur Durchführung bewertet. Hierbei wurden Lipidpatienten und Long-COVID-Patienten eingeschlossen. Nach Behandlung wurde eine Onlinebefragung zu Nutzung und Einschätzung durchgeführt. Ergebnisse 29,1 % der 134 Patienten wurden eingeschlossen behandelt (3 Ablehnungen). Alle Probanden (16 Antworten) berichteten, (sehr) gut zurechtgekommen zu sein. Vorteile wurden in Beratung und Nachbeobachtung gesehen. Probleme wurden hinsichtlich Technik und möglicher Störungen befürchtet. Datenschutzaspekte spielten eine untergeordnete Rolle. Im Vergleich mit dem Telefonat wurde eine signifikante Verbesserung für das Arzt-Patienten-Verhältnis (p-Wert = 0,00027), die Behandlungs- und Informationsqualität (p-Wert jeweils = 0,00044), den Versorgungszugang (p-Wert = 0,0053) und die Kommunikation (p-Wert = 0,021) angenommen. Im Vergleich mit dem persönlichen Kontakt wurde eine Verbesserung des Versorgungszugangs (p-Wert = 0,021) und der Informationsqualität gesehen (p-Wert = 0,034). Als Hauptprobleme wurden fehlende Erfahrungen, technische Anforderungen, technische Probleme und fehlende Pünktlichkeit der Behandler angeführt. Gelobt wurden Flexibilität, geringer Aufwand und die angenehme Konsultation. Alle Probanden wollten die Videosprechstunde weiterhin nutzen. Fazit Die Videosprechstunde kann eine Ergänzung der Versorgung von Lipidpatienten darstellen. Die korrekte Nutzung erfordert eine exakte Planung und weitere Forschung.

show abstract

Das Long-COVID-Syndrom – ein neues Krankheitsbild nach COVID-19-Infekt

Cited by 6 publications

References 48 publications

The pattern of cytokines expression and dynamic changes of renal function at 6 months in patients with Omicron COVID‐19

The pattern of cytokines expression and dynamic changes of renal function at 6 months in patients with Omicron COVID‐19

The Evaluation of Health Care Services for Children and Adolescents With Post–COVID-19 Condition: Protocol for a Prospective Longitudinal Study

Utilization of video consultation in cardiovascular lipid treatment

Contact Info

Product

Resources

About