Das posteriore reversible Enzephalopathiesyndrom

Fischer, Marlene; Schmutzhard, Erich

doi:10.1007/s00063-016-0175-7

Cited by 14 publications

(7 citation statements)

References 33 publications

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“…PRES is a clinicoradiological syndrome defined by the presence of headache, altered mentation, seizures, visual dysfunction and focal neurological deficits 1. PRES is commonly associated with hypertension, eclampsia, vasculitis, metabolic disturbances, thrombotic thrombocytopenic purpura, haemolytic uraemic syndrome and drugs such as chemotherapeutic agents and immunomodulatory therapy.…”

Section: Discussionmentioning

confidence: 99%

Posterior reversible encephalopathy syndrome (PRES) as a complication of Guillain-Barre’ syndrome (GBS)

Nabi¹,

Rajput

Badshah

et al. 2016

BMJ Case Reports

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A 17-year-old Pakistani female patient presented with acute onset flaccid quadriparesis with nerve conduction studies showing demyelinating polyneuropathy consistent with Guillain-Barre' syndrome. She was treated with 4 plasmapheresis sessions. She developed raised blood pressure, headache, visual loss and generalised seizures on the 13th day of admission. MRI of the brain on contrast showed findings of altered signals low on T1-weighted image, high on T2-weighted image and fluid-attenuated inversion recovery in the white matter of bilateral occipital, parietal and right frontal lobe consistent with posterior reversible encephalopathy syndrome. The patient was administered antiepileptic and antihypertensive drugs to control seizures and blood pressure. She was discharged in a stable state. On follow-up her visual loss had recovered completely and she had regained full motor strength in all four extremities after 6 weeks. Fresh MRI of the brain revealed complete resolution of lesions. Antihypertensive and antiepileptic medication was discontinued. She is independent in all her daily activities.

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Section: Discussionmentioning

confidence: 99%

Posterior reversible encephalopathy syndrome (PRES) as a complication of Guillain-Barre’ syndrome (GBS)

Nabi¹,

Rajput

Badshah

et al. 2016

BMJ Case Reports

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“…According to some publications, the location and distribution of edema may determine the severity. Based on fluid-attenuated inversion recovery (FLAIR) MRI, McKinney et al defined mild cases as those in which the edema affects the cortical and subcortical white matter, moderate cases as those in which there is confluent edema extending from the cortex to the deep white matter, and severe cases as those in which there is confluent edema extending from the cortex to the ventricle, hemorrhage, midline shift, herniation, mass effect, involvement of the cerebellum, brain stem, or basal nuclei (DBRE) [11][12][13][14][15][16]. Therefore, this case could be classified as mild, which might explain our patient's clinical improvement in response to treatment (Figure 1).…”

Section: Discussionmentioning

confidence: 99%

Initial Normotensive Presentation of a Primigravida With Posterior Reversible Encephalopathy Syndrome: A Case Report

Aduen-Carrillo¹,

Hernandez-Woodbine²,

Capriles³

et al. 2021

Cureus

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Posterior reversible encephalopathy syndrome (PRES) is a clinical-radiological entity characterized by variable neurological manifestations, primarily caused by pathophysiological changes related to cerebral autoregulation that result in radiologically evident vasogenic edema. It is usually associated with hypertensive states, but it is not exclusively related to those. A healthy 18-year-old primigravid woman with no proteinuria or hypertension on admission presented with normotensive PRES. She had an intense diffuse headache that preceded a generalized tonic-clonic seizure. Her neurological status deteriorated, and hypertension was detected afterward. Brain imaging revealed bilateral vasogenic edema in the occipital region. Magnesium sulfate and antihypertensive medications were administered. A cesarean section was performed, and her neurological symptoms subsequently improved, leading to discharge with no complications. This case highlights the importance of suspecting PRES in pregnant patients even in the absence of preeclampsia.

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“…PRES is a rare and possibly underdiagnosed syndrome, with no specific well-defined diagnostic criteria. Due to the lack of randomized studies, actual knowledge of this condition comes from case reports and retrospective studies [1] . PRES is characterized by several neurological signs and symptoms associated with typical imaging findings, corresponding to areas of vasogenic cerebral oedema [1] .…”

Section: Discussionmentioning

confidence: 99%

“…Due to the lack of randomized studies, actual knowledge of this condition comes from case reports and retrospective studies [1] . PRES is characterized by several neurological signs and symptoms associated with typical imaging findings, corresponding to areas of vasogenic cerebral oedema [1] . It is defined as a clinical-radiological entity, with acute/sub-acute onset of headache, visual disturbances, nausea/vomiting, altered mental status, seizures and focal signs, usually associated with arterial hypertension [1,2] .…”

Section: Discussionmentioning

confidence: 99%

“…PRES is characterized by several neurological signs and symptoms associated with typical imaging findings, corresponding to areas of vasogenic cerebral oedema [1] . It is defined as a clinical-radiological entity, with acute/sub-acute onset of headache, visual disturbances, nausea/vomiting, altered mental status, seizures and focal signs, usually associated with arterial hypertension [1,2] . Neuroimaging, in particular magnetic resonance findings, most often shows bilateral white matter oedema in the posterior vascular territories (parietal and occipital lobes) [2][3][4] .…”

Section: Discussionmentioning

confidence: 99%

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Posterior Reversible Encephalopathy Syndrome and Azathioprine

Vilas-Boas

Corte-Real

2019

European Journal of Case Reports in Internal Medicine

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Posterior reversible encephalopathy syndrome (PRES) is a rare syndrome that presents with neurological manifestations, often associated with arterial hypertension. Magnetic resonance imaging (MRI) shows bilateral white matter oedema in the posterior vascular territories. Immunosuppression, (pre) eclampsia and autoimmune diseases can be implicated. A 27-year-old woman, with mixed connective tissue disease under azathioprine, was admitted in the emergency room in status epilepticus and with severe hypertension. The MRI showed bilateral oedema in a pattern compatible with PRES. There was clinical improvement after azathioprine suspension. PRES is typically reversible with prompt recognition of the syndrome and its trigger. The association with azathioprine is rare.

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Das posteriore reversible Enzephalopathiesyndrom

Cited by 14 publications

References 33 publications

Posterior reversible encephalopathy syndrome (PRES) as a complication of Guillain-Barre’ syndrome (GBS)

Posterior reversible encephalopathy syndrome (PRES) as a complication of Guillain-Barre’ syndrome (GBS)

Initial Normotensive Presentation of a Primigravida With Posterior Reversible Encephalopathy Syndrome: A Case Report

Posterior Reversible Encephalopathy Syndrome and Azathioprine

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