Das Verhalten absorbierbarer Nahtmaterialien im infizierten Urin

Osterhage, H. R.

doi:10.1007/978-3-642-70524-3_5

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“…Whether there is a causative relation between inflammatory provocation and urothelia dispersed into deeper layers of the wall of the urinary bladder cannot be determined for sure. The observations of Osterhage et al [7,19] appear to confirm this. There seem to be two important contributory factors with non absorbable polypropylene threads: the tendency of the urothelium to sprout into the stab channels plus the pres ence of persisting inflammation.…”

Section: Discussionsupporting

confidence: 79%

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Behavior of Different Suture Materials in the Urinary Bladder of the Rabbit with Special Reference to Wound Healing, Epithelization and Crystallization

Hanke¹,

Timm²,

Falk³

et al. 1994

Urol Int

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Five urinary bladder incisions were performed in 16 rabbits and the defects closed by plain catgut 4-0, chromic catgut 4-0, polypropylene 4-0, polyglactin 910 4-0 and polyglactin 910 8-0 in the form of an all-layer suture, thereby obtaining a total of 80 suture sites. The running sutures in 8 animals were reviewed by light microscopy after 1, 2, 7 and 15 weeks, and in 8 additional animals after 3 days, 1,2,7 and 15 weeks by scanning electron microscopy. Moreover, we analyzed and compared the autopsy findings on gross inspection, the urinary sediments and urinary cultures of the individual animals. Scanning electron-microscopic evaluations showed that epithelization of the intraluminal suture portions can be accomplished after 3 days already. Reduced suture strength and rapid absorption of the suture material prevent later postoperative incrustations. Light-microscopic inspection of the segments of the bladder wall bearing this suture material suggests that a minor inflammatory tissue response around the suture material – with polyglactin 910 8-0 in particular – is more likely to enhance regeneration of the tunica muscularis and to prevent formation of cysts than seen with a long-standing highly inflammatory tissue response around the suture site of catgut threads. In the animal experiment, the polyglactin 910 suture has shown sufficient firmness and proved to be superior to any other suture material as regards the reaction to foreign bodies and inclination to incrustation. A thinner thread used for sutures in the efferent urinary tract would thus have to be given preference over others. Plain catgut, chromic catgut and polyglactin 910 sutures, 4-0 in strength, were found to be disadvantageous in the animal model. The nonabsorbable propylene thread turned out to be inadequate in urinary bladder surgery.

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Section: Discussionsupporting

confidence: 79%

“…Suture materials in the genitourinary tract are foreign bodies which attract both calcification and crystallization germs via direct contact with urine in relation to the time factor, thus hazarding the success of surgical intervention by lithogenesis, obstruction of the ducts and/or secondary infections [1][2][3][4][5][6][7],…”

Section: Introductionmentioning

confidence: 99%