2020
DOI: 10.1101/2020.12.16.423084
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Data Augmentation Through Monte Carlo Arithmetic Leads to More Generalizable Classification in Connectomics

Abstract: Machine learning models are commonly applied to human brain imaging datasets in an effort to associate function or structure with behaviour, health, or other individual phenotypes. Such models often rely on low-dimensional maps generated by complex processing pipelines. However, the numerical instabilities inherent to pipelines limit the fidelity of these maps and introduce computational bias. Monte Carlo Arithmetic, a technique for introducing controlled amounts of numerical noise, was used to perturb a struc… Show more

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Cited by 4 publications
(2 citation statements)
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“…Depending on the analytic goals, this could involve the aggregation of results (e.g., bagging) to generate composite findings, or the ensembling of results to improve prediction 54,55 . This has been recently demonstrated in brain imaging and numerical uncertainty 56,57 .…”
Section: Discussionmentioning
confidence: 79%
“…Depending on the analytic goals, this could involve the aggregation of results (e.g., bagging) to generate composite findings, or the ensembling of results to improve prediction 54,55 . This has been recently demonstrated in brain imaging and numerical uncertainty 56,57 .…”
Section: Discussionmentioning
confidence: 79%
“…The fact that the results observed across OS versions and FL perturbations arise from equally-valid numerical operations also suggests that the observed variability may contain meaningful signal. In particular, signal measured from these perturbations might be leveraged to enhance biomarkers, as suggested in [15] where augmenting a diffusion MRI dataset with numerically-perturbed samples was shown to improve age classification.…”
Section: Conclusion and Discussionmentioning
confidence: 99%